Literature DB >> 1436057

A second-generation linkage map of the human genome.

J Weissenbach1, G Gyapay, C Dib, A Vignal, J Morissette, P Millasseau, G Vaysseix, M Lathrop.   

Abstract

A linkage map of the human genome has been constructed based on the segregation analysis of 814 newly characterized polymorphic loci containing short tracts of (C-A)n repeats in a panel of DNAs from eight large families. Statistical linkage analysis placed 813 of the markers into 23 linkage groups corresponding to the 22 autosomes and the X chromosome; 605 show a heterozygosity above 0.7 and 553 could be ordered with odds ratios above 1,000:1. The distance spanned corresponds to approximately 90% of the estimated length of the human genome.

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Year:  1992        PMID： 1436057     DOI： 10.1038/359794a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  450 in total

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2.  A low mutation rate for chloroplast microsatellites.

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4.  An extensive analysis of Y-chromosomal microsatellite haplotypes in globally dispersed human populations.

Authors:  M Kayser; M Krawczak; L Excoffier; P Dieltjes; D Corach; V Pascali; C Gehrig; L F Bernini; J Jespersen; E Bakker; L Roewer; P de Knijff
Journal:  Am J Hum Genet       Date:  2001-03-16       Impact factor: 11.025

5.  On discovery, genomes, the Society, and society.

Authors:  R G Worton
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Review 6.  Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineages.

Authors:  D C Rubinsztein; B Amos; G Cooper
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-06-29       Impact factor: 6.237

7.  A paradigm for finding genes for a complex human trait: polycystic ovary syndrome and follistatin.

Authors:  K Odunsi; K K Kidd
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

8.  Variability in the interpretation of microsatellite patterns with different electrophoretic conditions.

Authors:  A C Santos; Y Yamaoka; D Y Graham; A R Sepulveda
Journal:  Mol Pathol       Date:  1999-10

9.  Meiotic recombination and flanking marker exchange at the highly unstable human minisatellite CEB1 (D2S90).

Authors:  J Buard; A C Shone; A J Jeffreys
Journal:  Am J Hum Genet       Date:  2000-06-26       Impact factor: 11.025

10.  Extent and distribution of linkage disequilibrium in three genomic regions.

Authors:  G R Abecasis; E Noguchi; A Heinzmann; J A Traherne; S Bhattacharyya; N I Leaves; G G Anderson; Y Zhang; N J Lench; A Carey; L R Cardon; M F Moffatt; W O Cookson
Journal:  Am J Hum Genet       Date:  2000-11-13       Impact factor: 11.025
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