Literature DB >> 806323

Growth hormone release inhibiting hormone: actions on thyrotrophin and prolactin secretion after thyrotrophinreleasing hormone.

D Carr, A Gomez-Pan, D R Weightman, V C Roy, R Hall, G M Besser, M O Thorner, A S McNeilly, A V Schally, A J Kastin, D H Coy.   

Abstract

The hypothalamic tetradecapeptide growth hormone release inhibiting hormone (GH-RIH) blocked the thyrotrophin response to thyrotrophin-releasing hormone (TRH) in normal people and in patients with primary hypothyroidism. This inhibition was dose related. The TRH-induced prolactin release was not affected by GH-RIH. This dissociation of the thyrotrophin and prolactin responses to TRH by GH-RIH suggests that there are different mechanisms for release of thyrotrophin and prolactin and that only the former is affected by GH-RIH.

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Year:  1975        PMID： 806323      PMCID： PMC1673632          DOI： 10.1136/bmj.3.5975.67

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  13 in total

1.  Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone.

Authors:  P Borgeat; F Labrie; J Drouin; A Bélanger; H Immer; K Sestanj; V Nelson; M Götz; A V Schally; D H Coy; E J Coy
Journal:  Biochem Biophys Res Commun       Date:  1974-02-27       Impact factor: 3.575

2.  Effects of growth-hormone release-inhibiting hormone on circulating glucagon, insulin, and growth hormone in normal, diabetic, acromegalic, and hypopituitary patients.

Authors:  C H Mortimer; W M Tunbridge; D Carr; L Yeomans; T Lind; D H Coy; S R Bloom; A Kastin; C N Mallinson; G M Besser; A V Schally; R Hall
Journal:  Lancet       Date:  1974-04-20       Impact factor: 79.321

3.  Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.

Authors:  S R Bloom; C H Mortimer; M O Thorner; G M Besser; R Hall; A Gomez-Pan; V M Roy; R C Russell; D H Coy; A J Kastin; A V Schally
Journal:  Lancet       Date:  1974-11-09       Impact factor: 79.321

4.  Action of growth-hormone-release inhibitory hormone in healthy men and in acromegaly.

Authors:  R Hall; G M Besser; A V Schally; D H Coy; D Evered; D J Goldie; A J Kastin; A S McNeilly; C H Mortimer; C Phenekos; W M Tunbridge; D Weightman
Journal:  Lancet       Date:  1973-09-15       Impact factor: 79.321

5.  Inhibition of insulin secretion by somatostatin.

Authors:  K G Alberti; N J Christensen; S E Christensen; A P Hansen; J Iversen; K Lundbaek; K Seyer-Hansen; H Orskov
Journal:  Lancet       Date:  1973-12-08       Impact factor: 79.321

6.  Effects of somatostatin on the secretion of thyrotropin and prolactin.

Authors:  W Vale; C Rivier; P Brazeau; R Guillemin
Journal:  Endocrinology       Date:  1974-10       Impact factor: 4.736

7.  The inhibition by somatostatin of the thyrotropin response to thyrotropin-releasing hormone in normal subjects.

Authors:  J Weeke; A P Hansen; K Lundbaek
Journal:  Scand J Clin Lab Invest       Date:  1974-04       Impact factor: 1.713

8.  Prolactin, TSH, LH and FSH responses to a combined LHRH-TRH test at different stages of the menstrual cycle.

Authors:  A S McNeilly; C Hagen
Journal:  Clin Endocrinol (Oxf)       Date:  1974-10       Impact factor: 3.478

9.  Binding of thyrotropin-releasing hormone to plasma membranes of bovine anterior pituitary gland (hormone receptor-adenylate cyclase-equilibrium constant-( 3 H)thyrotropin).

Authors:  F Labrie; N Barden; G Poirier; A De Lean
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

10.  Prolactin stimulation by thyrotropin-releasing hormone in a patient with isolated thyrotropin deficiency.

Authors:  R Sachson; S W Rosen; P Cuatrecasas; J Roth; A G Frantz
Journal:  N Engl J Med       Date:  1972-11-09       Impact factor: 91.245
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  13 in total

Review 1.  Thyroid hormones and growth hormone secretion.

Authors:  R Valcavi; M Zini; I Portioli
Journal:  J Endocrinol Invest       Date:  1992-04       Impact factor: 4.256

2.  The mechanism whereby growth hormone-release inhibiting hormone (somatostatin) inhibits food stimulated gastric acid secretion in the cat.

Authors:  M Albinus; E L Blair; E R Grund; J D Reed; D J Sanders; A Gomez-Pan; A V Schally; G M Besser
Journal:  Agents Actions       Date:  1975-10

Review 3.  Somatostatin--both hormone and neurotransmitter?

Authors:  R Luft; S Efendić; T Hökfelt
Journal:  Diabetologia       Date:  1978-01-14       Impact factor: 10.122

4.  Inhibition of gastrin gene expression by somatostatin.

Authors:  P S Karnik; S J Monahan; M M Wolfe
Journal:  J Clin Invest       Date:  1989-02       Impact factor: 14.808

5.  Effect of simultaneous administration of GHRH (1-40) and TRH on GH, PRL and TSH secretion in normal man.

Authors:  M Giusti; A Lomeo; G Mazzocchi; R Torre; M Monachesi; P Sessarego; R Attanasio; G Giordano
Journal:  J Endocrinol Invest       Date:  1986-12       Impact factor: 4.256

6.  Effect of 4 weeks of octreotide treatment on prolactin, thyroid stimulating hormone and thyroid hormones in acromegalic patients. A double blind placebo-controlled cross-over study.

Authors:  M Andersen; T B Hansen; J Bollerslev; P Bjerre; H D Schrøder; C Hagen
Journal:  J Endocrinol Invest       Date:  1995-12       Impact factor: 4.256

7.  Comparison of the inhibition of histamine- and pentagastrin-stimulated gastric acid secretion by somatostatin in the cat.

Authors:  M Albinus; J D Reed; A Gomez-Pan; A V Schally; D H Coy
Journal:  Agents Actions       Date:  1977-12

8.  Structure-activity relationships of eighteen somatostatin analogues on gastric secretion.

Authors:  M P Brown; D H Coy; A Gomez-Pan; B H Hirst; M Hunter; C Meyers; J D Reed; A V Schally; B Shaw
Journal:  J Physiol       Date:  1978-04       Impact factor: 5.182

9.  Plasma prolactin in juvenile diabetics. 24-h studies with somatostatin.

Authors:  K F Hanssen; S E Christensen; A P Hansen; K Lundbaek; P A Torjesen; J Weeke
Journal:  Diabetologia       Date:  1978-11       Impact factor: 10.122

10.  Effect of somatostatin on thyrotropin, prolactin, growth hormone and insulin responses to thyrotropin releasing hormone and arginine in healthy, hypothyroid and acromegalic subjects.

Authors:  N Faure; J H Dussault; A Nadeau; F Szots; H Guyda; F Labrie
Journal:  Can Med Assoc J       Date:  1977-09-03       Impact factor: 8.262
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