Literature DB >> 8052618

Characterization of the promoter region of the gene for the rat neutral and basic amino acid transporter and chromosomal localization of the human gene.

N Yan1, R Mosckovitz, L D Gerber, S Mathew, V V Murty, S S Tate, S Udenfriend.   

Abstract

The promoter region of the rat kidney neutral and basic amino acid transporter (NBAT) gene has been isolated and sequenced. The major transcription initiation site was mapped by primer extension. The entire promoter region and a set of 5' deletions within it were expressed at a high level in LLC-PK1 cells using the luciferase indicator gene. Positive and negative regulatory elements in the promoter region were observed. A human genomic clone of the transporter was also obtained and was used to localize the NBAT gene at the p21 region of chromosome 2.

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Year:  1994        PMID： 8052618      PMCID： PMC44439          DOI： 10.1073/pnas.91.16.7548

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

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4.  Structural arrangements of transcription control domains within the 5'-untranslated leader regions of the HIV-1 and HIV-2 promoters.

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5.  Mapping of the gene for interferon-inducible dsRNA-dependent protein kinase to chromosome region 2p21-22: a site of rearrangements in myeloproliferative disorders.

Authors:  S M Hanash; L Beretta; C L Barcroft; S Sheldon; T W Glover; D Ungar; N Sonenberg
Journal:  Genes Chromosomes Cancer       Date:  1993-09       Impact factor: 5.006

6.  DNA sequencing with chain-terminating inhibitors.

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Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

7.  Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor.

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8.  Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

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Authors:  R A Rupp; A E Sippel
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10.  Na+-independent transport of basic and zwitterionic amino acids in mouse blastocysts by a shared system and by processes which distinguish between these substrates.

Authors:  L J Van Winkle; A L Campione; J M Gorman
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  8 in total

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Authors:  M Palacín; C Mora; J Chillarón; M J Calonge; R Estévez; D Torrents; X Testar; A Zorzano; V Nunes; J Purroy; X Estivill; P Gasparini; L Bisceglia; L Zelante
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

2.  Evidence suggesting that the minimal functional unit of a renal cystine transporter is a heterodimer and its implications in cystinuria.

Authors:  S S Tate
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

3.  Cloning, functional expression and dietary regulation of the mouse neutral and basic amino acid transporter (NBAT).

Authors:  H Segawa; K Miyamoto; Y Ogura; H Haga; K Morita; K Katai; S Tatsumi; T Nii; Y Taketani; E Takeda
Journal:  Biochem J       Date:  1997-12-01       Impact factor: 3.857

4.  Interactions between the thiol-group reagent N-ethylmaleimide and neutral and basic amino acid transporter-related amino acid transport.

Authors:  G J Peter; A Davies; P W Watt; J Birrell; P M Taylor
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5.  Multiple components of arginine and phenylalanine transport induced in neutral and basic amino acid transporter-cRNA-injected Xenopus oocytes.

Authors:  G J Peter; I G Davidson; A Ahmed; L McIlroy; A R Forrester; P M Taylor
Journal:  Biochem J       Date:  1996-09-15       Impact factor: 3.857

6.  Assignment of the gene responsible for cystinuria (rBAT) and of markers D2S119 and D2S177 to 2p16 by fluorescence in situ hybridization.

Authors:  M J Calonge; M Nadal; S Calvano; X Testar; L Zelante; A Zorzano; X Estivill; P Gasparini; M Palacín; V Nunes
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7.  Localization, by linkage analysis, of the cystinuria type III gene to chromosome 19q13.1.

Authors:  L Bisceglia; M J Calonge; A Totaro; L Feliubadaló; S Melchionda; J García; X Testar; M Gallucci; A Ponzone; L Zelante; A Zorzano; X Estivill; P Gasparini; V Nunes; M Palacín
Journal:  Am J Hum Genet       Date:  1997-03       Impact factor: 11.025

8.  Genetic heterogeneity in cystinuria: the SLC3A1 gene is linked to type I but not to type III cystinuria.

Authors:  M J Calonge; V Volpini; L Bisceglia; F Rousaud; L de Sanctis; E Beccia; L Zelante; X Testar; A Zorzano; X Estivill
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-10       Impact factor: 11.205
  8 in total

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