Literature DB >> 8025073

Toxic side effects of local anaesthetics on the human cornea.

M Boljka1, G Kolar, J Vidensek.   

Abstract

The cytotoxic effects of 0.5% amethocaine (tetracaine) on the human cornea were investigated by scanning electron microscopy. The ultrastructural examination of epithelial cells showed damage of the cell membrane, rare-faction and loss of microvilli, deposits of amethocaine on the corneal surface and accelerated desquamation of superficial epithelial cells.

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Year:  1994        PMID: 8025073      PMCID: PMC504793          DOI: 10.1136/bjo.78.5.386

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  12 in total

1.  Side-effects of local anesthetics on the corneal epithelium of the rabbit eye.

Authors:  J P Harnisch; F Hoffmann; L Dumitrescu
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1975-10-17

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Authors:  T BEHRENDT
Journal:  Am J Ophthalmol       Date:  1956-01       Impact factor: 5.258

Review 4.  Molecular mechanisms of local anesthesia: a review.

Authors:  J F Butterworth; G R Strichartz
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Journal:  Cesk Oftalmol       Date:  1974-09

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Authors:  C Hilsdorf; G Zenklusen
Journal:  Klin Monbl Augenheilkd       Date:  1973-04       Impact factor: 0.700

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Authors:  P M Leuenberger
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1970

8.  Oxybuprocaine keratopathy: a preventable disease.

Authors:  E P Penna; K F Tabbara
Journal:  Br J Ophthalmol       Date:  1986-03       Impact factor: 4.638

9.  [Particularly rapid appearance of a severe toxic keratopathy caused by oxybuprocaine].

Authors:  G Jallet; S Cleirens; E Girard; A Béchetoille
Journal:  Bull Soc Ophtalmol Fr       Date:  1980 Apr-May

10.  Keratitis from abuse of corneal anaesthetics.

Authors:  H E Henkes; T N Waubke
Journal:  Br J Ophthalmol       Date:  1978-01       Impact factor: 4.638

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  6 in total

1.  Cytotoxic effect and possible mechanisms of Tetracaine on human corneal epithelial cells in vitro.

Authors:  Xin Pang; Ting-Jun Fan
Journal:  Int J Ophthalmol       Date:  2016-04-18       Impact factor: 1.779

Review 2.  Immunity and pain in the eye: focus on the ocular surface.

Authors:  Romina Mayra Lasagni Vitar; Filippo Bonelli; Paolo Rama; Giulio Ferrari
Journal:  Clin Exp Immunol       Date:  2022-04-04       Impact factor: 4.330

3.  Topical proparacaine abuse resulting in evisceration.

Authors:  Adnan Aksoy; Ahmet Metin Başkan; Lokman Aslan; Murat Aslankurt
Journal:  BMJ Case Rep       Date:  2013-04-22

4.  Topical ocular anesthetic abuse among Iranian welders: time for action.

Authors:  Ali Sharifi; Hamid Sharifi; Mohammad Karamouzian; Mahmoud Mokhtari; Hamidreza Hosein Esmaeili; Afshin Sarafi Nejad; Mohammad Rahmatian
Journal:  Middle East Afr J Ophthalmol       Date:  2013 Oct-Dec

5.  EFFECT OF LUBRICANTS ON CORNEAL THICKNESS AFTER VITRECTOMY.

Authors:  Diane T Siegel; G Baker Hubbard; Jiong Yan; Blaine Cribbs; Nieraj Jain; Steve Yeh; Diem Bui; Jesse Smith; Scott Barb; William Pearce; Laura Ward; Andrew M Hendrick
Journal:  Retina       Date:  2020-08       Impact factor: 3.975

Review 6.  Differentiating Urgent and Emergent Causes of Acute Red Eye for the Emergency Physician.

Authors:  Christopher J Gilani; Allen Yang; Marc Yonkers; Megan Boysen-Osborn
Journal:  West J Emerg Med       Date:  2017-03-03
  6 in total

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