Literature DB >> 1081854

Side-effects of local anesthetics on the corneal epithelium of the rabbit eye.

J P Harnisch, F Hoffmann, L Dumitrescu.   

Abstract

The toxic side-effects of 0.4% Novesine and Chibro-Kerakain were investigated by scanning- and transmission electron microscopy in 15 rabbit corneae each in intervals of 3, 6, 10, 15 and 60 mins. The lesions following Kerakain were larger and occurred earlier. After 60 mins, the specimens after Novesine application showed an almost complete repair process, whereas after Kerakain the epithelial surface appeared to be functionally impaired.

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Year:  1975        PMID： 1081854     DOI： 10.1007/bf00506644

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN： 0065-6100


  10 in total

1.  [Effect of surface anesthesia on the regeneration of corneal epithelium].

Authors:  H J KUCHLE
Journal:  Klin Monbl Augenheilkd Augenarztl Fortbild       Date:  1955

2.  Effect of topical anesthetics on regeneration of corneal epithelium.

Authors:  W G MARR; R WOOD; L SENTERFIT; S SIGELMAN
Journal:  Am J Ophthalmol       Date:  1957-04       Impact factor: 5.258

3.  Topical anesthesia in ophthalmology.

Authors:  J G LINN; E K VEY
Journal:  Am J Ophthalmol       Date:  1955-11       Impact factor: 5.258

4.  [The use of a new local anesthetic in ophthalmology].

Authors:  R WITMER
Journal:  Schweiz Med Wochenschr       Date:  1953-02-07

5.  The fine structure of the corneal epithelium.

Authors:  C PEDLER
Journal:  Exp Eye Res       Date:  1962-03       Impact factor: 3.467

6.  The normal surface of corneal epithelium: a scanning electron microscopic study.

Authors:  R R Pfister
Journal:  Invest Ophthalmol       Date:  1973-09

7.  [Ultrastructure of corneal epithelium after topical anesthesia].

Authors:  P M Leuenberger
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1973

8.  [Corneal damage due to novesine].

Authors:  C Hilsdorf; G Zenklusen
Journal:  Klin Monbl Augenheilkd       Date:  1973-04       Impact factor: 0.700

9.  The stereo ultrastructure of the external and internal surface of the cornea.

Authors:  S Blümcke; K Morgenroth
Journal:  J Ultrastruct Res       Date:  1967-06

10.  Benoxinate (dorsacaine) for rapid corneal anesthesia.

Authors:  H E SCHLEGEL; K C SWAN
Journal:  AMA Arch Ophthalmol       Date:  1954-05
  10 in total
  4 in total

1.  Topical proparacaine abuse resulting in evisceration.

Authors:  Adnan Aksoy; Ahmet Metin Başkan; Lokman Aslan; Murat Aslankurt
Journal:  BMJ Case Rep       Date:  2013-04-22

2.  Effect of topical anaesthesia on corneal epithelial fragility.

Authors:  L G Carney; D J O'Leary; M Millodot
Journal:  Int Ophthalmol       Date:  1984-06       Impact factor: 2.031

3.  Toxic side effects of local anaesthetics on the human cornea.

Authors:  M Boljka; G Kolar; J Vidensek
Journal:  Br J Ophthalmol       Date:  1994-05       Impact factor: 4.638

Review 4.  New Perspectives in the Pathophysiology and Treatment of Pain in Patients with Dry Eye Disease.

Authors:  Giuseppe Giannaccare; Carla Ghelardini; Alessandra Mancini; Vincenzo Scorcia; Lorenzo Di Cesare Mannelli
Journal:  J Clin Med       Date:  2021-12-25       Impact factor: 4.241
  4 in total

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