Literature DB >> 23608875

Topical proparacaine abuse resulting in evisceration.

Adnan Aksoy1, Ahmet Metin Başkan, Lokman Aslan, Murat Aslankurt.   

Abstract

A 72-year-old man was admitted to our clinic because of pain in the right eye. Corneal oedema, peripheral anterior synechiae formation and intraocular lens were determined in the right eye. The left eye was normal except for nuclear sclerosis. Intraocular pressure was 35 mm Hg in the right eye and 14 mm Hg in the left eye. The patient was diagnosed as having bullous keratopathy and glaucoma. He was treated with antiglaucoma drugs and artificial tears as an outpatient. Persistent keratopathy was observed at follow-up, despite adequate therapy. In the detailed anamnesis of the patient, we discovered that he had used a topical anaesthetic instead of the prescribed medicine owing to ocular pain. The patient was still using topical anaesthetic eye drops, despite warnings. Finally, evisceration was performed on his right eye because of corneal melting and perforation.

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Year:  2013        PMID: 23608875      PMCID: PMC3645785          DOI: 10.1136/bcr-2013-009539

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

1.  Side-effects of local anesthetics on the corneal epithelium of the rabbit eye.

Authors:  J P Harnisch; F Hoffmann; L Dumitrescu
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1975-10-17

2.  Topical anesthetic abuse.

Authors:  G O Rosenwasser; S Holland; S C Pflugfelder; M Lugo; D G Heidemann; W W Culbertson; H Kattan
Journal:  Ophthalmology       Date:  1990-08       Impact factor: 12.079

3.  Effects of proparacaine on actin cytoskeleton of corneal epithelium.

Authors:  B A Dass; H K Soong; B Lee
Journal:  J Ocul Pharmacol       Date:  1988

4.  Toxic keratopathy due to abuse of topical anesthetic drugs.

Authors:  Baris Yeniad; Serife Canturk; Fatma Esin Ozdemir; Nilufer Alparslan; Koray Akarcay
Journal:  Cutan Ocul Toxicol       Date:  2010-06       Impact factor: 1.820

5.  Toxicity of topical anesthetic agents to human keratocytes in vivo.

Authors:  L B Moreira; N Kasetsuwan; D Sanchez; S S Shah; L LaBree; P J McDonnell
Journal:  J Cataract Refract Surg       Date:  1999-07       Impact factor: 3.351

6.  Topical anesthetic abuse keratopathy: a commonly overlooked health care problem.

Authors:  Ayse Yagci; Banu Bozkurt; Sait Egrilmez; Melis Palamar; Banu Turgut Ozturk; Hamiyet Pekel
Journal:  Cornea       Date:  2011-05       Impact factor: 2.651

7.  Clinical findings in patients with topical anaesthetic abuse keratitis: a report of five cases.

Authors:  J M Katsimpris; M Sarantoulakou; A Kordelou; D Petkou; I K Petropoulos
Journal:  Klin Monbl Augenheilkd       Date:  2007-04       Impact factor: 0.700

8.  Toxic side effects of local anaesthetics on the human cornea.

Authors:  M Boljka; G Kolar; J Vidensek
Journal:  Br J Ophthalmol       Date:  1994-05       Impact factor: 4.638

9.  Severe toxic keratopathy secondary to topical anesthetic abuse.

Authors:  G Rocha; I Brunette; M Le François
Journal:  Can J Ophthalmol       Date:  1995-06       Impact factor: 1.882

  9 in total
  1 in total

Review 1.  Differentiating Urgent and Emergent Causes of Acute Red Eye for the Emergency Physician.

Authors:  Christopher J Gilani; Allen Yang; Marc Yonkers; Megan Boysen-Osborn
Journal:  West J Emerg Med       Date:  2017-03-03
  1 in total

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