Literature DB >> 8008304

Meconium-stained amniotic fluid: increased risk for adverse neonatal outcome.

M D Berkus1, O Langer, A Samueloff, E M Xenakis, N T Field, L E Ridgway.   

Abstract

OBJECTIVE: To determine the risk of adverse neonatal outcome associated with meconium-stained amniotic fluid independent of that related to antepartum or intrapartum abnormalities.
METHODS: A cohort of 2200 consecutive deliveries was examined and the fetal heart rate (FHR) tracings analyzed independently. Singleton term pregnancies without fatal malformations were stratified by the consistency of meconium and compared.
RESULTS: Moderate or thick meconium increased the risk for adverse outcome more than threefold (relative risk 3.2, 95% confidence interval 2.0-5.2). This risk was independent of fetal heart tracing abnormalities or maternal hypertensive, kidney, or heart disease.
CONCLUSION: Thick meconium alone should alert the physician to a high-risk fetal condition. This phenomenon requires continuous FHR monitoring and reassurance of fetal well-being by acid-base assessment or the equivalent, regardless of maternal disease status or the presence of abnormal FHR tracings.

Entities:  

Mesh:

Year:  1994        PMID: 8008304

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  12 in total

1.  Bacteria and endotoxin in meconium-stained amniotic fluid at term: could intra-amniotic infection cause meconium passage?

Authors:  Roberto Romero; Bo Hyun Yoon; Piya Chaemsaithong; Josef Cortez; Chan-Wook Park; Rogelio Gonzalez; Ernesto Behnke; Sonia S Hassan; Tinnakorn Chaiworapongsa; Lami Yeo
Journal:  J Matern Fetal Neonatal Med       Date:  2013-12-16

2.  Spectrophotometric analysis in umbilical cords of infants with meconium aspiration syndrome.

Authors:  Oguz Tuncer; Erdal Peker; Nihat Demir; Sinan Akbayram; Ercan Kirimi
Journal:  J Membr Biol       Date:  2013-06-07       Impact factor: 1.843

3.  The frequency of meconium-stained amniotic fluid increases as a function of the duration of labor.

Authors:  Kyung A Lee; Seung Mi Lee; Hye Jin Yang; Chan-Wook Park; Shali Mazaki-Tovi; Bo Hyun Yoon; Roberto Romero
Journal:  J Matern Fetal Neonatal Med       Date:  2011-03-17

Review 4.  Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections.

Authors:  Thitiporn Siriwachirachai; Ussanee S Sangkomkamhang; Pisake Lumbiganon; Malinee Laopaiboon
Journal:  Cochrane Database Syst Rev       Date:  2014-11-06

5.  The Scottish perinatal neuropathology study: clinicopathological correlation in early neonatal deaths.

Authors:  J C Becher; J E Bell; J W Keeling; N McIntosh; B Wyatt
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2004-09       Impact factor: 5.747

6.  Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome.

Authors:  Roberto Romero; Bo Hyun Yoon; Piya Chaemsaithong; Josef Cortez; Chan-Wook Park; Rogelio Gonzalez; Ernesto Behnke; Sonia S Hassan; Francesca Gotsch; Lami Yeo; Tinnakorn Chaiworapongsa
Journal:  J Matern Fetal Neonatal Med       Date:  2014-01-06

7.  Interpreting category II fetal heart rate tracings: does meconium matter?

Authors:  Heather A Frey; Methodius G Tuuli; Anthony L Shanks; George A Macones; Alison G Cahill
Journal:  Am J Obstet Gynecol       Date:  2014-06-17       Impact factor: 8.661

8.  Tracheal suction at birth in non-vigorous neonates born through meconium-stained amniotic fluid.

Authors:  Sushma Nangia; Anu Thukral; Deepak Chawla
Journal:  Cochrane Database Syst Rev       Date:  2021-06-16

9.  Intrapartum factors associated with neonatal hypoxic ischemic encephalopathy: a case-controlled study.

Authors:  Vanessa E Torbenson; Mary Catherine Tolcher; Kate M Nesbitt; Christopher E Colby; Sherif A El-Nashar; Bobbie S Gostout; Amy L Weaver; Michaela E Mc Gree; Abimbola O Famuyide
Journal:  BMC Pregnancy Childbirth       Date:  2017-12-11       Impact factor: 3.007

10.  Factors Leading To Meconium Aspiration Syndrome in Term- and Post-term Neonates.

Authors:  Saroop Chand; Aamna Salman; Razia Mustafa Abbassi; Abdul Rehman Siyal; Fayaz Ahmed; Abdul Lateef Leghari; Ashmal Sami Kabani; Sajid Ali
Journal:  Cureus       Date:  2019-09-05
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