Literature DB >> 21410421

The frequency of meconium-stained amniotic fluid increases as a function of the duration of labor.

Kyung A Lee1, Seung Mi Lee, Hye Jin Yang, Chan-Wook Park, Shali Mazaki-Tovi, Bo Hyun Yoon, Roberto Romero.   

Abstract

OBJECTIVE: The purpose of this study was to determine whether there is a relationship between the frequency of meconium-stained amniotic fluid (MSAF) and the duration of labor in term singleton gestation.
METHODS: The clinical characteristics of women who delivered term singleton live newborns between 2001 and 2006 were examined. The cases involving neonates with major congenital anomalies were excluded.
RESULTS: (1) The frequency of MSAF in term pregnancies was 18.4% (806/4376); (2) MSAF was found in only 2.8% (28/1008) of women who delivered by elective cesarean, but in 23.1% (778/3368) of women who delivered after the onset of labor (p < 0.001); (3) The longer the duration of labor (first stage, second stage, or total), the higher the frequency of MSAF (p < 0.001 for each); this remained significant after adjusting for other confounding variables such as parity, duration of rupture of membranes, gestational age at delivery, and mode of delivery (p < 0.001 for each).
CONCLUSION: MSAF was found in only 2.8% (28/1008) of women who delivered before the onset of labor, but in 23.1% (778/3368) of women who delivered after the onset of labor. The longer the duration of labor, the higher the risk of MSAF in term singleton gestation.

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Year:  2011        PMID: 21410421      PMCID: PMC3551273          DOI: 10.3109/14767058.2010.531329

Source DB:  PubMed          Journal:  J Matern Fetal Neonatal Med        ISSN: 1476-4954


  56 in total

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Review 2.  Meconium passage in utero: mechanisms, consequences, and management.

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3.  Meconium-stained amniotic fluid--perinatal outcome and obstetrical management in a low-risk suburban population.

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4.  Stress responses at birth: determinants of cord arterial cortisol and links with cortisol response in infancy.

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5.  Fetal plasma cortisol and dehydroepiandrosterone sulfate concentrations in pregnancy and term parturition.

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6.  Meconium-stained liquor during labor is associated with raised neonatal cord blood 8-iso-prostaglandin F2alpha concentration.

Authors:  Bao Yi Liu; Chi Chiu Wang; Tze Kin Lau; Ching Yan Chu; M Phil; Chi Pui Pang; Michael Scott Rogers; Tse Ngong Leung
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7.  Factors affecting the duration of the latency period in preterm premature rupture of membranes.

Authors:  Nir Melamed; Eran Hadar; Avi Ben-Haroush; Boris Kaplan; Yariv Yogev
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8.  Oropharyngeal and nasopharyngeal suctioning of meconium-stained neonates before delivery of their shoulders: multicentre, randomised controlled trial.

Authors:  Nestor E Vain; Edgardo G Szyld; Luis M Prudent; Thomas E Wiswell; Adriana M Aguilar; Norma I Vivas
Journal:  Lancet       Date:  2004 Aug 14-20       Impact factor: 79.321

9.  Pentraxin 3 in amniotic fluid: a novel association with intra-amniotic infection and inflammation.

Authors:  Laura Cruciani; Roberto Romero; Edi Vaisbuch; Juan Pedro Kusanovic; Tinnakorn Chaiworapongsa; Shali Mazaki-Tovi; Pooja Mittal; Giovanna Ogge; Francesca Gotsch; Offer Erez; Sun Kwon Kim; Zhong Dong; Percy Pacora; Ronald F Lamont; Lami Yeo; Sonia S Hassan; Gian Carlo Di Renzo
Journal:  J Perinat Med       Date:  2010-03       Impact factor: 1.901

10.  Amniotic fluid soluble human leukocyte antigen-G in term and preterm parturition, and intra-amniotic infection/inflammation.

Authors:  Juan Pedro Kusanovic; Roberto Romero; Cristiano Jodicke; Shali Mazaki-Tovi; Edi Vaisbuch; Offer Erez; Pooja Mittal; Francesca Gotsch; Tinnakorn Chaiworapongsa; Sam S Edwin; Percy Pacora; Sonia S Hassan
Journal:  J Matern Fetal Neonatal Med       Date:  2009-12
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  3 in total

1.  Bacteria and endotoxin in meconium-stained amniotic fluid at term: could intra-amniotic infection cause meconium passage?

Authors:  Roberto Romero; Bo Hyun Yoon; Piya Chaemsaithong; Josef Cortez; Chan-Wook Park; Rogelio Gonzalez; Ernesto Behnke; Sonia S Hassan; Tinnakorn Chaiworapongsa; Lami Yeo
Journal:  J Matern Fetal Neonatal Med       Date:  2013-12-16

2.  Meconium aspiration syndrome: a role for fetal systemic inflammation.

Authors:  JoonHo Lee; Roberto Romero; Kyung A Lee; Eun Na Kim; Steven J Korzeniewski; Piya Chaemsaithong; Bo Hyun Yoon
Journal:  Am J Obstet Gynecol       Date:  2015-10-17       Impact factor: 8.661

3.  Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome.

Authors:  Roberto Romero; Bo Hyun Yoon; Piya Chaemsaithong; Josef Cortez; Chan-Wook Park; Rogelio Gonzalez; Ernesto Behnke; Sonia S Hassan; Francesca Gotsch; Lami Yeo; Tinnakorn Chaiworapongsa
Journal:  J Matern Fetal Neonatal Med       Date:  2014-01-06
  3 in total

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