Literature DB >> 7979310

Evaluation of curative anticryptosporidial activity of paromomycin in a dexamethasone-treated rat model.

R Verdon1, J Polianski, C Gaudebout, C Marche, L Garry, J J Pocidalo.   

Abstract

A dexamethasone-treated rat model of cryptosporidiosis was used to evaluate the curative activity of paromomycin. Although eradication of the parasite could not be demonstrated, statistically significant decreases in oocyst excretion and in the intensity of ileal parasitism were observed in animals receiving 100 mg of paromomycin per kg of body weight per day.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7979310      PMCID： PMC284618          DOI： 10.1128/AAC.38.7.1681

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Activity of azithromycin against cryptosporidia in immunosuppressed rats.

Authors:  J E Rehg
Journal:  J Infect Dis       Date:  1991-06       Impact factor: 5.226

2.  Paromomycin for the treatment of cryptosporidial diarrhoea in AIDS patients.

Authors:  K Clezy; J Gold; J Blaze; P Jones
Journal:  AIDS       Date:  1991-09       Impact factor: 4.177

3.  Characterization of a dexamethasone-treated rat model of cryptosporidial infection.

Authors:  J E Rehg; M L Hancock; D B Woodmansee
Journal:  J Infect Dis       Date:  1988-12       Impact factor: 5.226

4.  Curative and preventive anticryptosporidium activities of sinefungin in an immunosuppressed adult rat model.

Authors:  P Brasseur; D Lemeteil; J J Ballet
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

5.  Paromomycin inhibits Cryptosporidium infection of a human enterocyte cell line.

Authors:  R J Marshall; T P Flanigan
Journal:  J Infect Dis       Date:  1992-04       Impact factor: 5.226

Review 6.  Cryptosporidiosis.

Authors:  W L Current; L S Garcia
Journal:  Clin Microbiol Rev       Date:  1991-07       Impact factor: 26.132

7.  Glycoside antibiotics alone and combined with tetracyclines for prophylaxis of experimental cryptosporidiosis in neonatal BALB/c mice.

Authors:  R Fayer; W Ellis
Journal:  J Parasitol       Date:  1993-08       Impact factor: 1.276

8.  Treatment of cryptosporidiosis with paromomycin. A report of five cases.

Authors:  K Armitage; T Flanigan; J Carey; I Frank; R R MacGregor; P Ross; R Goodgame; J Turner
Journal:  Arch Intern Med       Date:  1992-12

9.  Paromomycin is effective as prophylaxis for cryptosporidiosis in dairy calves.

Authors:  R Fayer; W Ellis
Journal:  J Parasitol       Date:  1993-10       Impact factor: 1.276

10.  Use of paromomycin for treatment of cryptosporidiosis in patients with AIDS.

Authors:  C J Fichtenbaum; D J Ritchie; W G Powderly
Journal:  Clin Infect Dis       Date:  1993-02       Impact factor: 9.079
  10 in total
  2 in total

1.  Synergistic anticryptosporidial potential of the combination alpha-1-antitrypsin and paromomycin.

Authors:  J R Forney; S Yang; M C Healey
Journal:  Antimicrob Agents Chemother       Date:  1997-09       Impact factor: 5.191

2.  Evaluation of high-dose regimen of paromomycin against cryptosporidiosis in the dexamethasone-treated rat model.

Authors:  R Verdon; J Polianski; C Gaudebout; C Marche; L Garry; C Carbon; J J Pocidalo
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.