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Literature DB >> 7975273

Nucleotide sequence of the P1 region of serotype Asia1 foot-and-mouth disease virus.

Y Stram¹, O Laor, T Molad, D Chai, D Moore, H Yadin, Y Becker.

Abstract

Differences in the amino acid sequence of foot-and-mouth disease virus (FMDV) virion proteins (VP) among the various FMDV serotypes, particularly in the VP1 polypeptide, are the basis for antigenic diversity of this virus group. This phenomenon provides the basis for type diagnosis of FMDV by the polymerase chain reaction (PCR). In order to specifically identify the Asia1 FMDV serotype by PCR, the nucleotide sequence of its P1-coding region was determined. The sequence exhibited over 70% homology with the P1 gene segment of type O1k. The deduced amino acid sequence shares 79% homology with that of the P1 region of serotype O1k.

Entities: Disease Species

Mesh：

Substances：

Year: 1994 PMID： 7975273 DOI： 10.1007/BF01704521

Source DB: PubMed Journal: Virus Genes ISSN： 0920-8569 Impact factor: 2.332

12 in total

1. The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution.

Authors: R Acharya; E Fry; D Stuart; G Fox; D Rowlands; F Brown
Journal: Nature Date: 1989-02-23 Impact factor: 49.962

2. All foot and mouth disease virus serotypes initiate protein synthesis at two separate AUGs.

Authors: D V Sangar; S E Newton; D J Rowlands; B E Clarke
Journal: Nucleic Acids Res Date: 1987-04-24 Impact factor: 16.971

3. Comparison of the nucleotide sequence at the 5' end of RNAs from nine aphthoviruses, including representatives of the Seven serotypes.

Authors: T J Harris
Journal: J Virol Date: 1980-12 Impact factor: 5.103

Nucleotide sequence of the P1 region of serotype Asia1 foot-and-mouth disease virus.

1. The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution.

2. All foot and mouth disease virus serotypes initiate protein synthesis at two separate AUGs.

3. Comparison of the nucleotide sequence at the 5' end of RNAs from nine aphthoviruses, including representatives of the Seven serotypes.

4. A comprehensive set of sequence analysis programs for the VAX.

5. Sequence variation in the gene for the immunogenic capsid protein VP1 of foot-and-mouth disease virus type A.

6. Direct method for quantitation of extreme polymerase error frequencies at selected single base sites in viral RNA.

7. Gene encoding capsid protein VP1 of foot-and-mouth disease virus: a quasispecies model of molecular evolution.

8. Nucleotide sequence and genome organization of foot-and-mouth disease virus.

9. Structure of a major immunogenic site on foot-and-mouth disease virus.

10. VP1 of serotype C foot-and-mouth disease viruses: long-term conservation of sequences.

1. Arginine-glycine-aspartic acid motif is critical for human parechovirus 1 entry.

2. VP1-coding sequences of recent isolates of foot-and-mouth disease virus types A, O and Asia1.

3. Antigenic variation in Foot and Mouth Disease Virus type Asia 1 isolates circulated during 1993-95 in India.

4. Capsid protein-encoding (P1) sequence of foot and mouth disease virus type Asia 1 ind 63/72.