A new 3D localization technique using quadratic field gradients.

A new method of 3D spatial selection using pulsed quadratic field gradients is presented. Like previous pulsed quadratic gradient methods the new method requires only two RF pulses to achieve selection in three dimensions. Unlike previous methods, however, precise alignment of linear and quadratic gradient coils is not required. This characteristic allows the method to be used with small or surface quadratic gradient coils. The method is demonstrated on phantom and rats.