Literature DB >> 7959027

A multifunctional vector family for gene expression in mammalian cells.

W Dirks1, F Schaper, S Kirchhoff, C Morelle, H Hauser.   

Abstract

A family of different promoters and vector backbones for multiple use in mammalian cells in vivo and in vitro experiments has been created. The elements allow high-level constitutive, as well as adjustable expression with mono- and dicistronic transcription units and several in vitro manipulations of the inserted ORFs. The vector components are designed to be combined in a simple cloning step.

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Year:  1994        PMID： 7959027     DOI： 10.1016/0378-1119(94)90186-4

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  11 in total

1.  Mature mRNAs accumulated in the nucleus are neither the molecules in transit to the cytoplasm nor constitute a stockpile for gene expression.

Authors:  D Weil; S Boutain; A Audibert; F Dautry
Journal:  RNA       Date:  2000-07       Impact factor: 4.942

2.  A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing.

Authors:  Dirk Spitzer; Jonathan E McDunn; Stacey Plambeck-Suess; Peter S Goedegebuure; Richard S Hotchkiss; William G Hawkins
Journal:  Mol Cancer Ther       Date:  2010-06-22       Impact factor: 6.261

3.  Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor.

Authors:  S Thiel; I Behrmann; A Timmermann; H Dahmen; G Müller-Newen; F Schaper; J Tavernier; V Pitard; P C Heinrich; L Graeve
Journal:  Biochem J       Date:  1999-04-01       Impact factor: 3.857

4.  Regulation of cell growth by IRF-1 in BHK-21 cells.

Authors:  S Kirchhoff; A Kröger; H Cruz; M Tümmler; F Schaper; M Köster; H Hauser
Journal:  Cytotechnology       Date:  1996-01       Impact factor: 2.058

5.  Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.

Authors:  F Schaper; C Gendo; M Eck; J Schmitz; C Grimm; D Anhuf; I M Kerr; P C Heinrich
Journal:  Biochem J       Date:  1998-11-01       Impact factor: 3.857

6.  Functional domains of interferon regulatory factor I (IRF-1).

Authors:  F Schaper; S Kirchhoff; G Posern; M Köster; A Oumard; R Sharf; B Z Levi; H Hauser
Journal:  Biochem J       Date:  1998-10-01       Impact factor: 3.857

7.  pQuattro vectors allow one-step multigene metabolic engineering and auto-selection of quattrocistronic artificial mammalian operons.

Authors:  M Fussenegger; S Moser; J E Bailey
Journal:  Cytotechnology       Date:  1998-11       Impact factor: 2.058

8.  Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response.

Authors:  Ulfert Rand; Melanie Rinas; Johannes Schwerk; Gesa Nöhren; Melanie Linnes; Andrea Kröger; Michael Flossdorf; Kristóf Kály-Kullai; Hansjörg Hauser; Thomas Höfer; Mario Köster
Journal:  Mol Syst Biol       Date:  2012-05-22       Impact factor: 11.429

9.  Regulated multicistronic expression technology for mammalian metabolic engineering.

Authors:  M Fussenegger; S Moser; J E Bailey
Journal:  Cytotechnology       Date:  1998-11       Impact factor: 2.058

10.  Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology.

Authors:  Katharina Tatzel; Lindsay Kuroki; Igor Dmitriev; Elena Kashentseva; David T Curiel; S Peter Goedegebuure; Matthew A Powell; David G Mutch; William G Hawkins; Dirk Spitzer
Journal:  Sci Rep       Date:  2016-03-03       Impact factor: 4.379
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