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Literature DB >> 7937054

Database and software for the analysis of mutations at the human p53 gene.

Abstract

A computerized database containing DNA sequence information regarding human p53 mutants has been created. The database itself is in the dBASE format and contains information on nearly 3000 mutants. In addition, an IBM PC compatible software package to analyze the information in the database has been developed. Both the database and software are freely available via the Internet.

Entities: Gene Species

Mesh：

Year: 1994 PMID： 7937054 PMCID： PMC308316

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

8 in total

Review 1. Structural aspects of the p53 protein in relation to gene evolution.

Authors: T Soussi; C Caron de Fromentel; P May
Journal: Oncogene Date: 1990-07 Impact factor: 9.867

2. p53 mutation in hepatocellular carcinoma after aflatoxin exposure.

Authors: M Ozturk
Journal: Lancet Date: 1991-11-30 Impact factor: 79.321

3. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa.

Authors: B Bressac; M Kew; J Wands; M Ozturk
Journal: Nature Date: 1991-04-04 Impact factor: 49.962

4. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

Authors: A Ziegler; D J Leffell; S Kunala; H W Sharma; M Gailani; J A Simon; A J Halperin; H P Baden; P E Shapiro; A E Bale
Journal: Proc Natl Acad Sci U S A Date: 1993-05-01 Impact factor: 11.205

5. Mutational hotspot in the p53 gene in human hepatocellular carcinomas.

Authors: I C Hsu; R A Metcalf; T Sun; J A Welsh; N J Wang; C C Harris
Journal: Nature Date: 1991-04-04 Impact factor: 49.962

Review 6. p53 mutations in human cancers.

Authors: M Hollstein; D Sidransky; B Vogelstein; C C Harris
Journal: Science Date: 1991-07-05 Impact factor: 47.728

Review 7. TP53 tumor suppressor gene: a model for investigating human mutagenesis.

Authors: C Caron de Fromentel; T Soussi
Journal: Genes Chromosomes Cancer Date: 1992-01 Impact factor: 5.006

8. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Authors: D E Brash; J A Rudolph; J A Simon; A Lin; G J McKenna; H P Baden; A J Halperin; J Pontén
Journal: Proc Natl Acad Sci U S A Date: 1991-11-15 Impact factor: 11.205

8 in total

10 in total

1. Dominant-negative p53 mutations selected in yeast hit cancer hot spots.

Authors: R K Brachmann; M Vidal; J D Boeke
Journal: Proc Natl Acad Sci U S A Date: 1996-04-30 Impact factor: 11.205

2. Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents.

Authors: N F Cariello; G R Douglas; N J Gorelick; D W Hart; J D Wilson; T Soussi
Journal: Nucleic Acids Res Date: 1998-01-01 Impact factor: 16.971

3. Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and both the lacI and lacZ gene in transgenic rodents.

Authors: N F Cariello; G R Douglas; M J Dycaico; N J Gorelick; G S Provost; T Soussi
Journal: Nucleic Acids Res Date: 1997-01-01 Impact factor: 16.971

4. Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and the lacZ gene in transgenic rodents.

Authors: N F Cariello; G R Douglas; T Soussi
Journal: Nucleic Acids Res Date: 1996-01-01 Impact factor: 16.971

5. Databases and QSAR for cancer research.

Authors: Adeel Malik; Hemajit Singh; Munazah Andrabi; Syed Akhtar Husain; Shandar Ahmad
Journal: Cancer Inform Date: 2007-02-15

6. Complete sequence of p53 gene in 20 patients with lung cancer: comparison with chemosensitivity and immunohistochemistry.

Authors: D Brattström; M Bergqvist; K Lamberg; W Kraaz; L Scheibenflug; G Gustafsson; M Inganäs; G Wagenius; O Brodin
Journal: Med Oncol Date: 1998-12 Impact factor: 3.064

7. Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin.

Authors: Dae-Hee Lee; Juong G Rhee; Yong J Lee
Journal: Br J Pharmacol Date: 2009-05-11 Impact factor: 8.739