| Literature DB >> 7931364 |
M J Salvatore1, O D Hensens, D L Zink, J Liesch, C Dufresne, J G Ondeyka, T M Jürgens, R P Borris, S Raghoobar, E McCauley.
Abstract
gamma-Pyrone-3-acetic acid (L-741,494) is a novel metabolite produced by a culture of the fungal genus Xylaria. This substance is a water-soluble, competitive, irreversible inhibitor of Interleukin-1 beta Converting Enzyme that is inactive against papain and trypsin. It has a mol wt of 154 and an empirical formula of C7H6O4. We propose the name xylaric acid for this compound.Entities:
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Year: 1994 PMID： 7931364 DOI： 10.1021/np50108a011
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050