Literature DB >> 7916700

Recent studies of ribonuclease P.

S Altman1, L Kirsebom, S Talbot.   

Abstract

RNase P is an essential enzyme that is required for the biosynthesis of tRNA. It is composed of RNA and protein subunits. The RNA subunit of the enzyme derived from eubacterial sources can carry out the catalytic function by itself in vitro. Current studies of RNase P focus on structure-function relationships with respect to interactions of the RNA subunit with its substrates and with respect to the determination of the kinetic parameters of the reaction, the role of the protein component, and the rules governing recognition of substrates.

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Year:  1993        PMID: 7916700     DOI: 10.1096/fasebj.7.1.7916700

Source DB:  PubMed          Journal:  FASEB J        ISSN: 0892-6638            Impact factor:   5.191


  58 in total

1.  A novel RNA-binding protein from Triturus carnifex identified by RNA-ligand screening with the newt hammerhead ribozyme.

Authors:  M A Denti; A E Martínez de Alba; R Sägesser; M Tsagris; M Tabler
Journal:  Nucleic Acids Res       Date:  2000-03-01       Impact factor: 16.971

2.  RNA-protein interactions in the human RNase MRP ribonucleoprotein complex.

Authors:  H Pluk; H van Eenennaam; S A Rutjes; G J Pruijn; W J van Venrooij
Journal:  RNA       Date:  1999-04       Impact factor: 4.942

3.  Cross-clade inhibition of HIV-1 replication and cytopathology by using RNase P-associated external guide sequences.

Authors:  Gunter Kraus; Rebeca Geffin; Gina Spruill; Andrea K Young; Rachel Seivright; Diana Cardona; Jennifer Burzawa; H James Hnatyszyn
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-19       Impact factor: 11.205

4.  Putative intermediary stages for the molecular evolution from a ribozyme to a catalytic RNP.

Authors:  Yoshiya Ikawa; Kentaro Tsuda; Shigeyoshi Matsumura; Shota Atsumi; Tan Inoue
Journal:  Nucleic Acids Res       Date:  2003-03-01       Impact factor: 16.971

5.  Kinetics of inhibition of ribonuclease P activity by peptidyltransferase inhibitors. Effect of antibiotics on RNase P.

Authors:  Dimitra Kalavrizioti; Anastassios Vourekas; Apostolos Tekos; Antigoni Tsagla; Constantinos Stathopoulos; Denis Drainas
Journal:  Mol Biol Rep       Date:  2003-03       Impact factor: 2.316

6.  Effect of peptidyltransferase inhibitors on ribonuclease P activity from Dictyostelium discoideum. Effect of antibiotics on RNase P.

Authors:  C Stathopoulos; A Tsagla; A Tekos; D Drainas
Journal:  Mol Biol Rep       Date:  2000-06       Impact factor: 2.316

Review 7.  Evolutionary perspective on the structure and function of ribonuclease P, a ribozyme.

Authors:  N R Pace; J W Brown
Journal:  J Bacteriol       Date:  1995-04       Impact factor: 3.490

8.  Artificial regulation of gene expression in Escherichia coli by RNase P.

Authors:  C Guerrier-Takada; Y Li; S Altman
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

9.  RPM2, independently of its mitochondrial RNase P function, suppresses an ISP42 mutant defective in mitochondrial import and is essential for normal growth.

Authors:  C K Kassenbrock; G J Gao; K R Groom; P Sulo; M G Douglas; N C Martin
Journal:  Mol Cell Biol       Date:  1995-09       Impact factor: 4.272

10.  Precursor of C4 antisense RNA of bacteriophages P1 and P7 is a substrate for RNase P of Escherichia coli.

Authors:  R K Hartmann; J Heinrich; J Schlegl; H Schuster
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

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