| Literature DB >> 7890250 |
W A Poppe1, P S Ide, M P Drijkoningen, J M Lauweryns, F A Van Assche.
Abstract
Previous reports have supported an association between tobacco smoking and cervical neoplasia. Our observations show an association between smoking and a reduction of the numerical densities of Langerhans cells and of helper/inducer T lymphocytes in the squamous epithelia of the transformation zone of the uterine cervix. This suggests a local impairment of cell-mediated immunity by smoking. This immunosuppressive effect could support the concept that smoking is an independent risk factor for cervical neoplasia.Entities:
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Year: 1995 PMID: 7890250 DOI: 10.1159/000292372
Source DB: PubMed Journal: Gynecol Obstet Invest ISSN: 0378-7346 Impact factor: 2.031