Literature DB >> 7885841

The genomic structure of the STAT genes: multiple exons in coincident sites in Stat1 and Stat2.

R Yan1, S Qureshi, Z Zhong, Z Wen, J E Darnell.   

Abstract

The genomic structure of Stat2 has been determined and compared with a large portion of the Stat1 gene. There are 24 exons in the Stat2 gene and a matching number in very similar positions in the Stat1 gene. Thus a very complicated genomic structure was presumably duplicated and has been closely maintained throughout evolution.

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Year:  1995        PMID： 7885841      PMCID： PMC306697          DOI： 10.1093/nar/23.3.459

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  26 in total

1.  Selection of splice sites in pre-mRNAs with short internal exons.

Authors:  Z Dominski; R Kole
Journal:  Mol Cell Biol       Date:  1991-12       Impact factor: 4.272

Review 2.  A survey on intron and exon lengths.

Authors:  J D Hawkins
Journal:  Nucleic Acids Res       Date:  1988-11-11       Impact factor: 16.971

3.  Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element.

Authors:  N Reich; B Evans; D Levy; D Fahey; E Knight; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

4.  Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.

Authors:  D E Levy; D S Kessler; R Pine; J E Darnell
Journal:  Genes Dev       Date:  1989-09       Impact factor: 11.361

5.  The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

Authors:  B J Wagner; T E Hayes; C J Hoban; B H Cochran
Journal:  EMBO J       Date:  1990-12       Impact factor: 11.598

6.  Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6.

Authors:  Z Zhong; Z Wen; J E Darnell
Journal:  Science       Date:  1994-04-01       Impact factor: 47.728

7.  Synergistic action of interleukin-6 and glucocorticoids is mediated by the interleukin-6 response element of the rat alpha 2 macroglobulin gene.

Authors:  G M Hocke; D Barry; G H Fey
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

8.  DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes.

Authors:  A Tanaka; C P Gibbs; R R Arthur; S K Anderson; H J Kung; D J Fujita
Journal:  Mol Cell Biol       Date:  1987-05       Impact factor: 4.272

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3.

Authors:  D E Levy; D J Lew; T Decker; D S Kessler; J E Darnell
Journal:  EMBO J       Date:  1990-04       Impact factor: 11.598
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  15 in total

Review 1.  The role of signal transducer and activator of transcription-2 in the interferon response.

Authors:  Håkan C Steen; Ana M Gamero
Journal:  J Interferon Cytokine Res       Date:  2012-01-26       Impact factor: 2.607

2.  A JAK-STAT pathway regulates wing vein formation in Drosophila.

Authors:  R Yan; H Luo; J E Darnell; C R Dearolf
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

3.  NFAR-1 and -2 modulate translation and are required for efficient host defense.

Authors:  Ingrid Pfeifer; Rachel Elsby; Marilyn Fernandez; Paula A Faria; Daniel R Nussenzveig; Izidor S Lossos; Beatriz M A Fontoura; W David Martin; Glen N Barber
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-12       Impact factor: 11.205

4.  Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma.

Authors:  J F Bromberg; C M Horvath; Z Wen; R D Schreiber; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-23       Impact factor: 11.205

5.  DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites.

Authors:  U Vinkemeier; S L Cohen; I Moarefi; B T Chait; J Kuriyan; J E Darnell
Journal:  EMBO J       Date:  1996-10-15       Impact factor: 11.598

6.  Functional differences between Stat3alpha and Stat3beta.

Authors:  T S Schaefer; L K Sanders; O K Park; D Nathans
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

7.  Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells.

Authors:  A R Karpf; P W Peterson; J T Rawlins; B K Dalley; Q Yang; H Albertsen; D A Jones
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-23       Impact factor: 11.205

8.  RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins.

Authors:  Shu Xiao; Dong Li; Hai-Qing Zhu; Man-Gen Song; Xiao-Rong Pan; Pei-Min Jia; Lin-Ling Peng; Ai-Xia Dou; Guo-Qiang Chen; Sai-Juan Chen; Zhu Chen; Jian-Hua Tong
Journal:  Proc Natl Acad Sci U S A       Date:  2006-10-18       Impact factor: 11.205

9.  Naturally occurring dominant negative variants of Stat5.

Authors:  D Wang; D Stravopodis; S Teglund; J Kitazawa; J N Ihle
Journal:  Mol Cell Biol       Date:  1996-11       Impact factor: 4.272

10.  Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses.

Authors:  Timothy Hoey; Shangming Zhang; Nathan Schmidt; Qing Yu; Shyam Ramchandani; Xiang Xu; Lisa K Naeger; Ya-Lin Sun; Mark H Kaplan
Journal:  EMBO J       Date:  2003-08-15       Impact factor: 11.598
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