Literature DB >> 7877600

Antioxidant properties of dehydrozingerone and curcumin in rat brain homogenates.

D V Rajakumar1, M N Rao.   

Abstract

The present study investigates the inhibition of lipid peroxidation by dehydrozingerone and curcumin in rat brain homogenates. Both the test compounds inhibited the formation of conjugated dienes and spontaneous lipid peroxidation. These compounds also inhibited lipid peroxidation induced by ferrous ions, ferric-ascorbate and ferric-ADP-ascorbate. In all these cases, curcumin was more active than dehydrozingerone and dl-alpha-tocopherol.

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Year:  1994        PMID： 7877600     DOI： 10.1007/bf00928368

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  29 in total

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Authors:  M Ciuffi; G Gentilini; S Franchi-Micheli; L Zilletti
Journal:  Neurochem Res       Date:  1991-01       Impact factor: 3.996

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Journal:  Lancet       Date:  1984-06-23       Impact factor: 79.321

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Journal:  Chem Pharm Bull (Tokyo)       Date:  1985-04       Impact factor: 1.645

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Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

5.  Oxygen radical scavenging activity of phenylbutenones and their correlation with antiinflammatory activity.

Authors:  L A Saldanha; G Elias; M N Rao
Journal:  Arzneimittelforschung       Date:  1990-01

Review 6.  Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin.

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Review 7.  Mechanisms of drug actions against neuronal damage caused by ischemia--an overview.

Authors:  B Peruche; J Krieglstein
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  1993-01       Impact factor: 5.067

Review 8.  Free radicals in medicine. I. Chemical nature and biologic reactions.

Authors:  P A Southorn; G Powis
Journal:  Mayo Clin Proc       Date:  1988-04       Impact factor: 7.616

9.  Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin.

Authors:  K K Soudamini; M C Unnikrishnan; K B Soni; R Kuttan
Journal:  Indian J Physiol Pharmacol       Date:  1992-10

10.  Induction of glutathione S-transferase activity by curcumin in mice.

Authors:  M Susan; M N Rao
Journal:  Arzneimittelforschung       Date:  1992-07
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  8 in total

1.  Molecular dynamics simulations and binding free energy analysis of DNA minor groove complexes of curcumin.

Authors:  Mathew Varghese Koonammackal; Unnikrishnan Viswambharan Nair Nellipparambil; Chellappanpillai Sudarsanakumar
Journal:  J Mol Model       Date:  2011-02-02       Impact factor: 1.810

2.  Effect of dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats.

Authors:  Mallikarjuna C Rao; Arun T Sudheendra; Pawan G Nayak; Piya Paul; Gopalan N Kutty; Rekha R Shenoy
Journal:  Mol Cell Biochem       Date:  2011-05-13       Impact factor: 3.396

3.  Synthesis and antibacterial activity of novel curcumin derivatives containing heterocyclic moiety.

Authors:  Othman A Hamed; Noha Mehdawi; Adham Abu Taha; Emad M Hamed; Mohammed A Al-Nuri; Ayman S Hussein
Journal:  Iran J Pharm Res       Date:  2013       Impact factor: 1.696

4.  The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

Authors:  G P Lim; T Chu; F Yang; W Beech; S A Frautschy; G M Cole
Journal:  J Neurosci       Date:  2001-11-01       Impact factor: 6.167

5.  Alkyne-azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors via the PI3K/Akt/NF-kB pathway.

Authors:  Chetan Kumar; Reyaz Ur Rasool; Zainab Iqra; Yedukondalu Nalli; Prabhu Dutt; Naresh K Satti; Neha Sharma; Sumit G Gandhi; Anindya Goswami; Asif Ali
Journal:  Medchemcomm       Date:  2017-11-02       Impact factor: 3.597

6.  Dehydrozingerone exerts beneficial metabolic effects in high-fat diet-induced obese mice via AMPK activation in skeletal muscle.

Authors:  Su Jin Kim; Hong Min Kim; Eun Soo Lee; Nami Kim; Jung Ok Lee; Hye Jeong Lee; Na Yeon Park; Joo Yeon Jo; Bo Young Ham; Si Hyun Han; Sun Hwa Park; Choon Hee Chung; Hyeon Soo Kim
Journal:  J Cell Mol Med       Date:  2015-01-12       Impact factor: 5.310

Review 7.  Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review.

Authors:  Xiu-Fen Liu; Ji-Long Hao; Tian Xie; Nour Jama Mukhtar; Wiley Zhang; Tayyab Hamid Malik; Cheng-Wei Lu; Dan-Dan Zhou
Journal:  Front Pharmacol       Date:  2017-02-14       Impact factor: 5.810

8.  Dehydrozingerone inhibits renal lipotoxicity in high-fat diet-induced obese mice.

Authors:  Eun Soo Lee; Jeong Suk Kang; Hong Min Kim; Su Jin Kim; Nami Kim; Jung Ok Lee; Hyeon Soo Kim; Eun Young Lee; Choon Hee Chung
Journal:  J Cell Mol Med       Date:  2021-08-12       Impact factor: 5.310
  8 in total

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