| Literature DB >> 1418063 |
Abstract
Curcumin, a natural constituent of Curcuma longa (turmeric, CAS 458-37-7), has been studied for its induction of glutathione S-transferase activity in mice. At a dose of 250 mg/kg orally for 15 days, the enzyme activity in liver was increased by 1.8 fold. Its effect on other tissues like stomach, small intestine, lungs, kidney was not significant. Curcumin also depleted sulfhydryl levels in tissues, especially in stomach where 45% depletion was observed.Entities:
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Year: 1992 PMID： 1418063
Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172