Literature DB >> 7869044

Chemoattraction of human blood T lymphocytes by interleukin-15.

P C Wilkinson1, F Y Liew.   

Abstract

Recombinant interleukin (IL)-15, derived from a simian kidney epithelial cell line, is a chemoattractant for human blood T lymphocytes judged by its ability to increase the proportion of cells in polarized morphology, to stimulate invasion of collagen gels containing IL-15, and to increase the proportion of locomotor cells observed by time-lapse videorecording. The ability of lymphocytes to respond was partly, but not completely, inhibited by pretreatment with anti-IL-2 receptor beta-chain. The activity of IL-15 was completely abolished by preincubation with aIL-15 but unaffected by preincubation with aIL-2. No response of monocytes, neutrophils, or B lymphocytes to IL-15 was observed.

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Year:  1995        PMID: 7869044      PMCID: PMC2191928          DOI: 10.1084/jem.181.3.1255

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  20 in total

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2.  The locomotor capacity of human lymphocytes and its enhancement by cell growth.

Authors:  P C Wilkinson
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3.  OKT3-activated locomotion of human blood lymphocytes: a phenomenon requiring contact of T cells with Fc receptor-bearing cells.

Authors:  P C Wilkinson; A Higgins
Journal:  Immunology       Date:  1987-03       Impact factor: 7.397

4.  Neutrophil leucocyte chemotaxis: a simplified assay for measuring polarizing responses to chemotactic factors.

Authors:  W S Haston; J M Shields
Journal:  J Immunol Methods       Date:  1985-08-02       Impact factor: 2.303

5.  Separation and purification of lymphocyte chemotactic factor (LCF) and interleukin 2 produced by human peripheral blood mononuclear cells.

Authors:  J W Potter; D E Van Epps
Journal:  Cell Immunol       Date:  1987-03       Impact factor: 4.868

6.  Chemoattractant activity of IL-2 for human lymphocytes: a requirement for the IL-2 receptor beta-chain.

Authors:  P C Wilkinson; I Newman
Journal:  Immunology       Date:  1994-05       Impact factor: 7.397

7.  Induction of human T lymphocyte motility by interleukin 2.

Authors:  H Kornfeld; J S Berman; D J Beer; D M Center
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8.  Interleukin-2 in rheumatoid arthritis: production of and response to interleukin-2 in rheumatoid synovial fluid, synovial tissue and peripheral blood.

Authors:  B Combe; R M Pope; M Fischbach; B Darnell; S Baron; N Talal
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9.  Purification of human monocytes on microexudate-coated surfaces.

Authors:  S K Ackerman; S D Douglas
Journal:  J Immunol       Date:  1978-04       Impact factor: 5.422

10.  Collagen substrata for studies on cell behavior.

Authors:  T Elsdale; J Bard
Journal:  J Cell Biol       Date:  1972-09       Impact factor: 10.539

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  53 in total

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Review 3.  The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use.

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5.  The picture of the prostatic lymphokine network is becoming increasingly complex.

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Journal:  Rev Urol       Date:  2002

6.  A role for IL-15 in the migration of effector CD8 T cells to the lung airways following influenza infection.

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7.  Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants.

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8.  Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa.

Authors:  Madeleine D Hu; Alexander D Ethridge; Rebecca Lipstein; Sushil Kumar; Yitang Wang; Bana Jabri; Jerrold R Turner; Karen L Edelblum
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9.  The bacterial superantigen Staphylococcal enterotoxin B stimulates lymphocyte locomotor capacity during culture in vitro.

Authors:  I Newman; P C Wilkinson
Journal:  Immunology       Date:  1996-03       Impact factor: 7.397

10.  Cytokine profile during latent and slowly progressive primary tuberculosis: a possible role for interleukin-15 in mediating clinical disease.

Authors:  F Abebe; T Mustafa; A H Nerland; G A Bjune
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