Literature DB >> 7809169

Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum.

K Goto1, M Funayama, H Kondo.   

Abstract

A third species of diacylglycerol kinase (EC 2.7.1.107) cDNA was cloned from a rat brain cDNA library. The isolated cDNA encoded a 788-amino acid, 88-kDa polypeptide. This isozyme shared 58% identity with the previously isolated rat 80-kDa and 90-kDa diacylglycerol kinases. EF hand motifs, cysteine-rich zinc finger-like sequences, and putative ATP-binding site were all conserved among these isozymes. The 88-kDa diacylglycerol kinase was expressed specifically in brain and localized predominantly in cerebellar Purkinje cells. This isozyme was associated equally with particulate and supernatant fractions in cDNA-transfected COS-7 cells and dominantly with the particulate fraction in the brain. After Triton X-100 extraction, this isozyme remained in the detergent-insoluble cytoskeletal fraction of the brain and transfected COS-7 cells.

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Year:  1994        PMID： 7809169      PMCID： PMC45577          DOI： 10.1073/pnas.91.26.13042

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  26 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 2.  The molecular heterogeneity of protein kinase C and its implications for cellular regulation.

Authors:  Y Nishizuka
Journal:  Nature       Date:  1988-08-25       Impact factor: 49.962

3.  Occurrence of immunoreactive 80 kDa and non-immunoreactive diacylglycerol kinases in different pig tissues.

Authors:  K Yamada; H Kanoh
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

4.  Brain phospholipase C isozymes: differential mRNA localizations by in situ hybridization.

Authors:  C A Ross; M W MacCumber; C E Glatt; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

5.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

Authors:  P Chomczynski; N Sacchi
Journal:  Anal Biochem       Date:  1987-04       Impact factor: 3.365

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  Diacylglycerol-induced translocation of diacylglycerol kinase: use of affinity-purified enzyme in a reconstitution system.

Authors:  J M Besterman; R S Pollenz; E L Booker; P Cuatrecasas
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells.

Authors:  F A Wiegant; F J Blok; L H Defize; W A Linnemans; A J Verkley; J Boonstra
Journal:  J Cell Biol       Date:  1986-07       Impact factor: 10.539

10.  Association of the epidermal growth factor receptor kinase with the detergent-insoluble cytoskeleton of A431 cells.

Authors:  G E Landreth; L K Williams; G D Rieser
Journal:  J Cell Biol       Date:  1985-10       Impact factor: 10.539
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  22 in total

1.  Expression and localization of type II diacylglycerol kinase isozymes δ and η in the developing mouse brain.

Authors:  Takako Usuki; Hiromichi Sakai; Takao Shionoya; Naruki Sato; Fumio Sakane
Journal:  J Histochem Cytochem       Date:  2014-10-31       Impact factor: 2.479

Review 2.  Signaling at the membrane interface by the DGK/SK enzyme family.

Authors:  Daniel M Raben; Binks W Wattenberg
Journal:  J Lipid Res       Date:  2008-12-09       Impact factor: 5.922

3.  Induction of filopodia-like protrusions in N1E-115 neuroblastoma cells by diacylglycerol kinase γ independent of its enzymatic activity: potential novel function of the C-terminal region containing the catalytic domain of diacylglycerol kinase γ.

Authors:  Fumihiko Tanino; Yuki Maeda; Hiromichi Sakai; Fumio Sakane
Journal:  Mol Cell Biochem       Date:  2012-10-08       Impact factor: 3.396

4.  Involvement of diacylglycerol kinase γ in modulation of iNOS synthesis in Golgi apparatus of vascular endothelial cells.

Authors:  Tomoyuki Nakano; Yasukazu Hozumi; Kaoru Goto; Ichiro Wakabayashi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2012-05-25       Impact factor: 3.000

5.  Molecular cloning of a cDNA encoding diacylglycerol kinase (DGK) in Arabidopsis thaliana.

Authors:  T Katagiri; T Mizoguchi; K Shinozaki
Journal:  Plant Mol Biol       Date:  1996-02       Impact factor: 4.076

6.  Purification and characterization of sn-1-stearoyl-2-arachidonoylglycerol kinase from pig testes.

Authors:  M N Hodgkin; S D Gardner; S Rose; A Paterson; A Martin; M J Wakelam
Journal:  Biochem J       Date:  1997-03-01       Impact factor: 3.857

7.  A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus.

Authors:  K Goto; H Kondo
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

8.  Developmentally expressed myosin heavy-chain kinase possesses a diacylglycerol kinase domain.

Authors:  C D Thanos; J U Bowie
Journal:  Protein Sci       Date:  1996-04       Impact factor: 6.725

9.  Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.

Authors:  Donghui Li; Aarti N Urs; Jeremy Allegood; Adam Leon; Alfred H Merrill; Marion B Sewer
Journal:  Mol Cell Biol       Date:  2007-07-30       Impact factor: 4.272

10.  Signaling cascade of diacylglycerol kinase β in the pituitary intermediate lobe: dopamine D2 receptor/phospholipase Cβ4/diacylglycerol kinase β/protein kinase Cα.

Authors:  Yasukazu Hozumi; Masahiko Watanabe; Kaoru Goto
Journal:  J Histochem Cytochem       Date:  2010-02       Impact factor: 2.479
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