Literature DB >> 7809162

The iron-responsive element binding protein: a target for synaptic actions of nitric oxide.

S R Jaffrey1, N A Cohen, T A Rouault, R D Klausner, S H Snyder.   

Abstract

Molecular targets for the actions of nitric oxide (NO) have only been partially clarified. The dynamic properties of the iron-sulfur (Fe-S) cluster of the iron responsive-element binding protein (IRE-BP) suggested that it might serve as a target for NO produced in response to glutamatergic stimulation in neurons. In the present study, we demonstrate that N-methyl-D-aspartate, acting through NO, stimulates the RNA-binding function of the IRE-BP in brain slices while diminishing its aconitase activity. In addition, we demonstrate a selective localization of the IRE-BP in discrete neuronal structures, suggesting a potential role for this protein in the response of neurons to NO.

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Year:  1994        PMID： 7809162      PMCID： PMC45567          DOI： 10.1073/pnas.91.26.12994

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  42 in total

1.  Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

Authors:  D S Bredt; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

Review 2.  Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication.

Authors:  S Moncada; R M Palmer; E A Higgs
Journal:  Biochem Pharmacol       Date:  1989-06-01       Impact factor: 5.858

3.  Purification of a specific repressor of ferritin mRNA translation from rabbit liver.

Authors:  W E Walden; M M Patino; L Gaffield
Journal:  J Biol Chem       Date:  1989-08-15       Impact factor: 5.157

4.  Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

Authors:  D S Bredt; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

5.  Mitochondrial hexokinase. Release, rebinding, and location.

Authors:  I A Rose; J V Warms
Journal:  J Biol Chem       Date:  1967-04-10       Impact factor: 5.157

6.  G protein mRNA mapped in rat brain by in situ hybridization.

Authors:  B L Largent; D T Jones; R R Reed; R C Pearson; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

Review 7.  Endothelium-derived relaxing and contracting factors.

Authors:  R F Furchgott; P M Vanhoutte
Journal:  FASEB J       Date:  1989-07       Impact factor: 5.191

8.  NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices.

Authors:  J Garthwaite; G Garthwaite; R M Palmer; S Moncada
Journal:  Eur J Pharmacol       Date:  1989-10-17       Impact factor: 4.432

9.  A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA.

Authors:  E W Müllner; B Neupert; L C Kühn
Journal:  Cell       Date:  1989-07-28       Impact factor: 41.582

10.  Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3' untranslated region of the mRNA.

Authors:  J L Casey; D M Koeller; V C Ramin; R D Klausner; J B Harford
Journal:  EMBO J       Date:  1989-12-01       Impact factor: 11.598
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  12 in total

1.  Impact of endogenous nitric oxide on microglial cell energy metabolism and labile iron pool.

Authors:  Benoît Chénais; Hamid Morjani; Jean-Claude Drapier
Journal:  J Neurochem       Date:  2002-05       Impact factor: 5.372

2.  Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death.

Authors:  A Sawa; A A Khan; L D Hester; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-14       Impact factor: 11.205

3.  Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways.

Authors:  U K Messmer; B Brüne
Journal:  Biochem J       Date:  1996-10-01       Impact factor: 3.857

4.  Cloning and expression of two brain-specific inwardly rectifying potassium channels.

Authors:  D S Bredt; T L Wang; N A Cohen; W B Guggino; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205

Review 5.  Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

Authors:  M W Hentze; L C Kühn
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-06       Impact factor: 11.205

Review 6.  Signaling by gasotransmitters.

Authors:  Asif K Mustafa; Moataz M Gadalla; Solomon H Snyder
Journal:  Sci Signal       Date:  2009-04-28       Impact factor: 8.192

7.  Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats.

Authors:  Tetyana Khomenko; Sandor Szabo; Xiaoming Deng; Hideki Ishikawa; Gregory J Anderson; Gordon D McLaren
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2009-04-02       Impact factor: 4.052

8.  S-Nitrosylation of Divalent Metal Transporter 1 Enhances Iron Uptake to Mediate Loss of Dopaminergic Neurons and Motoric Deficit.

Authors:  Chao Liu; Cheng-Wu Zhang; Shun Qiang Lo; Seok Ting Ang; Katherine Chee Meng Chew; Dejie Yu; Bing Han Chai; Bobby Tan; Fai Tsang; Yee Kit Tai; Bryce Wei Quan Tan; Mui Cheng Liang; Hwee Tong Tan; Jia Ying Tang; Mitchell Kim Peng Lai; John Jia En Chua; Maxey Ching Ming Chung; Sanjay Khanna; Kah-Leong Lim; Tuck Wah Soong
Journal:  J Neurosci       Date:  2018-08-13       Impact factor: 6.167

9.  Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

Authors:  Scott Ayton; Peng Lei; Dominic J Hare; James A Duce; Jessica L George; Paul A Adlard; Catriona McLean; Jack T Rogers; Robert A Cherny; David I Finkelstein; Ashley I Bush
Journal:  J Neurosci       Date:  2015-02-25       Impact factor: 6.167

10.  Iron and Oxidative Stress in Parkinson's Disease: An Observational Study of Injury Biomarkers.

Authors:  Marcio S Medeiros; Arthur Schumacher-Schuh; Andreia Machado Cardoso; Guilherme Vargas Bochi; Jucimara Baldissarelli; Aline Kegler; Daniel Santana; Carolina Maria Martins Behle Soares Chaves; Maria Rosa Chitolina Schetinger; Rafael Noal Moresco; Carlos R M Rieder; Michele Rechia Fighera
Journal:  PLoS One       Date:  2016-01-11       Impact factor: 3.240
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