Literature DB >> 778987

Sulindac in osteoarthrosis of the hip.

P A Dieppe, H C Burry, R Grahame, T Perera.   

Abstract

Sulindac (400 mg/day) has been compared with ibuprofen (1200 mg/day) in 40 patients with osteoarthrosis of the hip, over an eight-week period, in a double-blind controlled clinical trial. The two drugs were comparable in terms of patient preference, effects on hip movements, and toxicity. Sulindac showed superior analgesic properties to ibuprofen, resulting in a significantly greater reduction in pain on weight-bearing and with passive movements (P less than 0.01).

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Year:  1976        PMID: 778987     DOI: 10.1093/rheumatology/15.2.112

Source DB:  PubMed          Journal:  Rheumatol Rehabil        ISSN: 0300-3396


  4 in total

Review 1.  Sulindac: a review of its pharmacological properties and therapeutic efficacy in rheumatic diseases.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-08       Impact factor: 9.546

2.  A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.

Authors:  R E Pemberton; L J Strand
Journal:  Dig Dis Sci       Date:  1979-01       Impact factor: 3.199

3.  Outcome measurement in osteoarthritis clinical trials: the case for standardisation.

Authors:  N Bellamy; W W Buchanan
Journal:  Clin Rheumatol       Date:  1984-09       Impact factor: 2.980

4.  Sulindac. Trials of a new anti-inflammatory drug.

Authors:  E C Huskisson; J Scott
Journal:  Ann Rheum Dis       Date:  1978-02       Impact factor: 19.103

  4 in total

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