Literature DB >> 6488707

Outcome measurement in osteoarthritis clinical trials: the case for standardisation.

N Bellamy, W W Buchanan.   

Abstract

Outcome measures for clinical trials to be valid and reliable should also be responsive to change. There are currently no standardised methods of measuring the outcome in osteoarthritis clinical trials. A review of 63 trials of nonsteroidal anti-inflammatory drugs revealed a large degree of variability in the items, instruments and scales employed. The implications of this variability are discussed and methods proposed for rationalising outcome measurement in this area of clinical research.

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Year:  1984        PMID： 6488707     DOI： 10.1007/bf02032334

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  85 in total

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Authors:  J LANSBURY
Journal:  Arthritis Rheum       Date:  1958-12

2.  Statistical study of variation in systemic and articular indexes.

Authors:  J LANSBURY; H N BAIER; S McCRACKEN
Journal:  Arthritis Rheum       Date:  1962-10

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Journal:  Can Med Assoc J       Date:  1937-06       Impact factor: 8.262

4.  Diflunisal and aspirin: a comparison of efficacy and nephrotoxicity in osteoarthritis.

Authors:  P A Dieppe; E C Huskisson
Journal:  Rheumatol Rehabil       Date:  1979-02

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Authors:  P L Boardman; G Nuki; F D Hart
Journal:  Ann Rheum Dis       Date:  1967-11       Impact factor: 19.103

6.  Accuracy of subjective measurements made with or without previous scores: an important source of error in serial measurement of subjective states.

Authors:  J Scott; E C Huskisson
Journal:  Ann Rheum Dis       Date:  1979-12       Impact factor: 19.103

7.  Double-blind study of ketoprofen against a placebo in osteoarthritis of the hip.

Authors:  M Caroit; B Forette; A Hubault; P Pasquier
Journal:  Scand J Rheumatol Suppl       Date:  1976

8.  Sulindac. Trials of a new anti-inflammatory drug.

Authors:  E C Huskisson; J Scott
Journal:  Ann Rheum Dis       Date:  1978-02       Impact factor: 19.103

9.  Fenoprofen therapy in large-joint osteoarthritis: double-blind comparison with aspirin and longterm experience.

Authors:  J W Brooke
Journal:  J Rheumatol       Date:  1976       Impact factor: 4.666

10.  Method for assessing therapeutic potential of anti-inflammatory antirheumatic drugs in rheumatoid arthritis.

Authors:  P Lee; J Webb; J Anderson; W W Buchanan
Journal:  Br Med J       Date:  1973-06-23
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  17 in total

1.  Effect of a glucosamine-based combination supplement containing chondroitin sulfate and antioxidant micronutrients in subjects with symptomatic knee osteoarthritis: A pilot study.

Authors:  Yasushi Nakasone; Kazunori Watabe; Keita Watanabe; Akihito Tomonaga; Isao Nagaoka; Tetsuro Yamamoto; Hideyo Yamaguchi
Journal:  Exp Ther Med       Date:  2011-06-27       Impact factor: 2.447

2.  Chondroprotective drugs and osteoarthritis.

Authors:  P Ghosh
Journal:  Ann Rheum Dis       Date:  1990-05       Impact factor: 19.103

3.  A preliminary evaluation of the dimensionality and clinical importance of pain and disability in osteoarthritis of the hip and knee.

Authors:  N Bellamy; W W Buchanan
Journal:  Clin Rheumatol       Date:  1986-06       Impact factor: 2.980

4.  Double-blind randomized controlled trial of isoxicam vs piroxicam in elderly patients with osteoarthritis of the hip and knee.

Authors:  N Bellamy; W W Buchanan; E Grace
Journal:  Br J Clin Pharmacol       Date:  1986       Impact factor: 4.335

5.  Electroacupuncture with different current intensities to treat knee osteoarthritis: a single-blinded controlled study.

Authors:  Ziyong Ju; Xianhui Guo; Xu Jiang; Xin Wang; Shimin Liu; Jinsen He; Huashun Cui; Ke Wang
Journal:  Int J Clin Exp Med       Date:  2015-10-15

Review 6.  'Natural remedies' in the treatment of osteoarthritis.

Authors:  Karen Walker-Bone
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

7.  An evaluation of the effectiveness of a videotape programme on interobserver reliability in outcome assessment for osteoarthritis.

Authors:  N Bellamy; C Anjema; N Alikhan; T Chhina; D Dhanoa; D Edelist; Z Esufali; F Ismail; J Hill; J Campbell
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 4.473

8.  Occurrence of symptomatic knee osteoarthrosis in rural Finland: a prospective follow up study.

Authors:  P Kannus; M Järvinen; H Kontiala; L Bergius; E Hyssy; E Salminen; A Tuomi; T Unkila; I Valtanen
Journal:  Ann Rheum Dis       Date:  1987-11       Impact factor: 19.103

9.  Relationship between severity and clinical importance of symptoms in osteoarthritis.

Authors:  N Bellamy; G Wells; J Campbell
Journal:  Clin Rheumatol       Date:  1991-06       Impact factor: 2.980

10.  Depression and somatisation influence the outcome of total hip replacement.

Authors:  Wolfgang Riediger; Stephan Doering; Martin Krismer
Journal:  Int Orthop       Date:  2008-11-26       Impact factor: 3.075
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