Literature DB >> 7773298

Nomenclature for N-acetyltransferases.

K P Vatsis1, W W Weber, D A Bell, J M Dupret, D A Evans, D M Grant, D W Hein, H J Lin, U A Meyer, M V Relling.   

Abstract

A consolidated classification system is described for prokaryotic and eukaryotic N-acetyltransferases in accordance with the international rules for gene nomenclature. The root symbol (NAT) specifically identifies the genes that code for the N-acetyltransferases, and NAT* loci encoding proteins with similar function are distinguished by Arabic numerals. Allele characters, denoted by Arabic numbers or by a combination of Arabic numbers and uppercase Latin letters, are separated from gene loci by an asterisk, and the entire gene-allele symbols are italicized. Alleles at the different NAT* loci have been numbered chronologically irrespective of the species of origin. For designation of genotypes at a single NAT* locus, a slash serves to separate the alleles; in phenotype designations, which are not italicized, alleles are separated by a comma.

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Year:  1995        PMID: 7773298     DOI: 10.1097/00008571-199502000-00001

Source DB:  PubMed          Journal:  Pharmacogenetics        ISSN: 0960-314X


  68 in total

Review 1.  Good genes, oxidative stress and condition-dependent sexual signals.

Authors:  T von Schantz; S Bensch; M Grahn; D Hasselquist; H Wittzell
Journal:  Proc Biol Sci       Date:  1999-01-07       Impact factor: 5.349

2.  N-acetyltransferases: pharmacogenetics and clinical consequences of polymorphic drug metabolism.

Authors:  S P Spielberg
Journal:  J Pharmacokinet Biopharm       Date:  1996-10

3.  A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid.

Authors:  C A Smith; M Wadelius; A C Gough; D J Harrison; C R Wolf; A Rane
Journal:  J Med Genet       Date:  1997-09       Impact factor: 6.318

4.  Thiopurine metabolites variations during co-treatment with aminosalicylates for inflammatory bowel disease: effect of N-acetyl transferase polymorphisms.

Authors:  Gabriele Stocco; Eva Cuzzoni; Sara De Iudicibus; Diego Favretto; Noelia Malusà; Stefano Martelossi; Elena Pozzi; Paolo Lionetti; Alessandro Ventura; Giuliana Decorti
Journal:  World J Gastroenterol       Date:  2015-03-28       Impact factor: 5.742

5.  N-Acetyltransferase polymorphism and human cancer risk.

Authors:  X Yang; T Takeshita; K Morimoto
Journal:  Environ Health Prev Med       Date:  2000-01       Impact factor: 3.674

Review 6.  Molecular basis of polymorphic drug metabolism.

Authors:  A K Daly
Journal:  J Mol Med (Berl)       Date:  1995-11       Impact factor: 4.599

Review 7.  Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist?

Authors:  D W Nebert
Journal:  Am J Hum Genet       Date:  1997-02       Impact factor: 11.025

8.  Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype.

Authors:  David W Hein; Mark A Doll
Journal:  Arch Toxicol       Date:  2017-05-18       Impact factor: 5.153

9.  The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers.

Authors:  N Rothman; V K Bhatnagar; R B Hayes; T V Zenser; S K Kashyap; M A Butler; D A Bell; V Lakshmi; M Jaeger; R Kashyap; A Hirvonen; P A Schulte; M Dosemeci; F Hsu; D J Parikh; B B Davis; G Talaska
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

10.  Analysis association between mitochondrial genome instability and xenobiotic metabolizing genes in human breast cancer.

Authors:  Walter H Pavicic; Martin Laguens; Silvina M Richard
Journal:  Mol Med       Date:  2009-03-06       Impact factor: 6.354

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