Literature DB >> 7736691

Concentration-controlled trials. What does the future hold?

A Johnston1, D W Holt.   

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Year:  1995        PMID: 7736691     DOI: 10.2165/00003088-199528020-00001

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN: 0312-5963            Impact factor:   6.447


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  41 in total

Review 1.  The impact of pharmacokinetically guided dose escalation strategies in phase I clinical trials: critical evaluation and recommendations for future studies.

Authors:  M A Graham; P Workman
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2.  Use of adaptive control with feedback to individualize suramin dosing.

Authors:  H I Scher; D I Jodrell; J M Iversen; T Curley; W Tong; M J Egorin; A Forrest
Journal:  Cancer Res       Date:  1992-01-01       Impact factor: 12.701

3.  Concentration-controlled versus concentration-defined clinical trials.

Authors:  G Levy
Journal:  Clin Pharmacol Ther       Date:  1993-03       Impact factor: 6.875

4.  Therapeutic response in phase I trials of antineoplastic agents.

Authors:  E Estey; D Hoth; R Simon; S Marsoni; B Leyland-Jones; R Wittes
Journal:  Cancer Treat Rep       Date:  1986-09

5.  Suramin, an active drug for prostate cancer: interim observations in a phase I trial.

Authors:  M A Eisenberger; L M Reyno; D I Jodrell; V J Sinibaldi; K H Tkaczuk; R Sridhara; E G Zuhowski; M H Lowitt; S C Jacobs; M J Egorin
Journal:  J Natl Cancer Inst       Date:  1993-04-21       Impact factor: 13.506

6.  Compliance during treatment of epilepsy.

Authors:  I E Leppik
Journal:  Epilepsia       Date:  1988       Impact factor: 5.864

7.  Application of pharmacokinetically guided dose escalation with respect to cell cycle phase specificity.

Authors:  E Fuse; S Kobayashi; M Inaba; H Suzuki; Y Sugiyama
Journal:  J Natl Cancer Inst       Date:  1994-07-06       Impact factor: 13.506

8.  Predictability of phenytoin serum levels by nomograms and clinicians.

Authors:  S Vozeh; A Koelz; E Martin; H Magun; G Scollo-Lavizzari; F Follath
Journal:  Eur Neurol       Date:  1980       Impact factor: 1.710

9.  A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group.

Authors:  R H Mattson; J A Cramer; J F Collins
Journal:  N Engl J Med       Date:  1992-09-10       Impact factor: 91.245

10.  Phase I and pharmacokinetic study of LM985 (flavone acetic acid ester).

Authors:  D J Kerr; S B Kaye; J Graham; J Cassidy; M Harding; A Setanoians; J C McGrath; W R Vezin; D Cunningham; G Forrest
Journal:  Cancer Res       Date:  1986-06       Impact factor: 12.701

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Review 1.  Therapeutic drug monitoring of immunosuppressant drugs.

Authors:  A Johnston; D W Holt
Journal:  Br J Clin Pharmacol       Date:  1999-04       Impact factor: 4.335

Review 2.  Concentration-controlled or effect-controlled trials: useful alternatives to conventional dose-controlled trials?

Authors:  A Grahnén; M O Karlsson
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

Review 3.  Integrated pharmacokinetics and pharmacodynamics in drug development.

Authors:  Jasper Dingemanse; Silke Appel-Dingemanse
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Review 4.  Target concentration strategy for cyclosporin monitoring.

Authors:  R G Morris
Journal:  Clin Pharmacokinet       Date:  1997-03       Impact factor: 6.447

5.  Imipramine and mirtazapine are less effective than expected.

Authors:  R M Pinder; M Zivkov
Journal:  Psychopharmacology (Berl)       Date:  1997-02       Impact factor: 4.530

Review 6.  Optimizing Mycophenolic Acid Exposure in Kidney Transplant Recipients: Time for Target Concentration Intervention.

Authors:  David K Metz; Nick Holford; Joshua Y Kausman; Amanda Walker; Noel Cranswick; Christine E Staatz; Katherine A Barraclough; Francesco Ierino
Journal:  Transplantation       Date:  2019-10       Impact factor: 4.939

  6 in total

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