K Harish1, R Ravi. 1. Department of Genito-urinary Surgery, Cancer Institute (WIA), Adyar, Madras, India.
Abstract
OBJECTIVE: To study the role of tobacco in squamous cell carcinoma of the penis. SUBJECTS AND METHODS: The use of tobacco in the form of cigarettes, chewing tobacco and snuff was studied in a total of 503 patients and age-matched controls. RESULTS: By multivariate analysis, a significant association was found between smoking (P = 0.002) or chewing tobacco (P < 0.001) and the use of snuff (P = 0.004) in patients with penile carcinoma as compared with controls. A dose-response relationship was observed for both smoking and chewing. CONCLUSIONS: The use of tobacco is a significant risk factor for penile carcinoma, and the use of more than one form of tobacco increases this risk.
OBJECTIVE: To study the role of tobacco in squamous cell carcinoma of the penis. SUBJECTS AND METHODS: The use of tobacco in the form of cigarettes, chewing tobacco and snuff was studied in a total of 503 patients and age-matched controls. RESULTS: By multivariate analysis, a significant association was found between smoking (P = 0.002) or chewing tobacco (P < 0.001) and the use of snuff (P = 0.004) in patients with penile carcinoma as compared with controls. A dose-response relationship was observed for both smoking and chewing. CONCLUSIONS: The use of tobacco is a significant risk factor for penile carcinoma, and the use of more than one form of tobacco increases this risk.
Authors: M C G Bleeker; D A M Heideman; P J F Snijders; S Horenblas; J Dillner; C J L M Meijer Journal: World J Urol Date: 2008-07-08 Impact factor: 3.661