Literature DB >> 7712293

Domain movements in protein kinases.

S Cox1, E Radzio-Andzelm, S S Taylor.   

Abstract

Structural studies of the catalytic subunit of the cAMP-dependent protein kinase, both by crystallographic methods and in solution, reveal two conformations. Crystal structures of several other protein kinases have also been solved in the past year. With this combined information we can begin to define mobile domains and subdomains within the conserved catalytic core.

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Year:  1994        PMID： 7712293     DOI： 10.1016/0959-440x(94)90272-0

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  34 in total

1.  Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange.

Authors:  A N Hoofnagle; K A Resing; E J Goldsmith; N G Ahn
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-30       Impact factor: 11.205

Review 2.  Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations.

Authors:  Buyong Ma; Maxim Shatsky; Haim J Wolfson; Ruth Nussinov
Journal:  Protein Sci       Date:  2002-02       Impact factor: 6.725

3.  Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme.

Authors:  K Niefind; B Guerra; I Ermakowa; O G Issinger
Journal:  EMBO J       Date:  2001-10-01       Impact factor: 11.598

4.  The crystal structure of the Physarum polycephalum actin-fragmin kinase: an atypical protein kinase with a specialized substrate-binding domain.

Authors:  S Steinbacher; P Hof; L Eichinger; M Schleicher; J Gettemans; J Vandekerckhove; R Huber; J Benz
Journal:  EMBO J       Date:  1999-06-01       Impact factor: 11.598

5.  The crystal structures of chloramphenicol phosphotransferase reveal a novel inactivation mechanism.

Authors:  T Izard; J Ellis
Journal:  EMBO J       Date:  2000-06-01       Impact factor: 11.598

6.  Phosphorylation-dependent changes in structure and dynamics in ERK2 detected by SDSL and EPR.

Authors:  Andrew N Hoofnagle; James W Stoner; Thomas Lee; Sandra S Eaton; Natalie G Ahn
Journal:  Biophys J       Date:  2004-01       Impact factor: 4.033

7.  On the evaluation and optimization of protein X-ray structures for pKa calculations.

Authors:  Jens Erik Nielsen; J Andrew McCammon
Journal:  Protein Sci       Date:  2003-02       Impact factor: 6.725

8.  Crystal structure of the plasmid maintenance system epsilon/zeta: functional mechanism of toxin zeta and inactivation by epsilon 2 zeta 2 complex formation.

Authors:  Anton Meinhart; Juan C Alonso; Norbert Sträter; Wolfram Saenger
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-05       Impact factor: 11.205

9.  Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain.

Authors:  Claudia Mertens; Minghao Zhong; Ravi Krishnaraj; Wenxin Zou; Xiaomin Chen; James E Darnell
Journal:  Genes Dev       Date:  2006-12-15       Impact factor: 11.361

10.  Crystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coli.

Authors:  Nicholas O'Toole; João A R G Barbosa; Yunge Li; Li-Wei Hung; Allan Matte; Miroslaw Cygler
Journal:  Protein Sci       Date:  2003-02       Impact factor: 6.725
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