Literature DB >> 7707558

Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro.

T Yoshinaga1, T Fujiwara.   

Abstract

To investigate the roles of bases near the tips of each strand of the long terminal repeat of the human immunodeficiency virus type 1 in the integration reaction, we examined the efficiencies of both binding and integration activities of staggered-ended substrates and mismatched mutant substrates by the integration assay and the UV cross-linking assay. Our results suggest that some bases of the human immunodeficiency virus type 1 long terminal repeat are required primarily for binding, whereas others are more critical for later reaction steps in vitro.

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Year:  1995        PMID： 7707558      PMCID： PMC189032     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites.

Authors:  F D Bushman; R Craigie
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

2.  Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting.

Authors:  M J Roth; P Schwartzberg; N Tanese; S P Goff
Journal:  J Virol       Date:  1990-10       Impact factor: 5.103

3.  Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence.

Authors:  M J Roth; P L Schwartzberg; S P Goff
Journal:  Cell       Date:  1989-07-14       Impact factor: 41.582

4.  Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

Authors:  P O Brown; B Bowerman; H E Varmus; J M Bishop
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

5.  DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.

Authors:  F M van den Ent; C Vink; R H Plasterk
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

6.  Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity.

Authors:  P A Sherman; J A Fyfe
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

7.  The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro.

Authors:  R Craigie; T Fujiwara; F Bushman
Journal:  Cell       Date:  1990-08-24       Impact factor: 41.582

8.  The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration.

Authors:  M Katzman; R A Katz; A M Skalka; J Leis
Journal:  J Virol       Date:  1989-12       Impact factor: 5.103

9.  Retroviral DNA integration: structure of an integration intermediate.

Authors:  T Fujiwara; K Mizuuchi
Journal:  Cell       Date:  1988-08-12       Impact factor: 41.582

10.  Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration.

Authors:  T Fujiwara; R Craigie
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205
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  13 in total

1.  Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration.

Authors:  Supachai Sakkhachornphop; Carlos F Barbas; Rassamee Keawvichit; Kanlaya Wongworapat; Chatchai Tayapiwatana
Journal:  Hum Gene Ther       Date:  2012-05-08       Impact factor: 5.695

2.  Integration of rous sarcoma virus DNA: a CA dinucleotide is not required for integration of the U3 end of viral DNA.

Authors:  Jangsuk Oh; Kevin W Chang; Stephen H Hughes
Journal:  J Virol       Date:  2008-09-03       Impact factor: 5.103

3.  Designed zinc finger protein interacting with the HIV-1 integrase recognition sequence at 2-LTR-circle junctions.

Authors:  Supachai Sakkhachornphop; Supat Jiranusornkul; Kanchanok Kodchakorn; Sawitree Nangola; Thira Sirisanthana; Chatchai Tayapiwatana
Journal:  Protein Sci       Date:  2009-11       Impact factor: 6.725

4.  Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction.

Authors:  D Esposito; R Craigie
Journal:  EMBO J       Date:  1998-10-01       Impact factor: 11.598

5.  Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase.

Authors:  W E Robinson; M G Reinecke; S Abdel-Malek; Q Jia; S A Chow
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

6.  Influence of subterminal viral DNA nucleotides on differential susceptibility to cleavage by human immunodeficiency virus type 1 and visna virus integrases.

Authors:  M Katzman; M Sudol
Journal:  J Virol       Date:  1996-12       Impact factor: 5.103

7.  Specific and independent recognition of U3 and U5 att sites by human immunodeficiency virus type 1 integrase in vivo.

Authors:  T Masuda; M J Kuroda; S Harada
Journal:  J Virol       Date:  1998-10       Impact factor: 5.103

8.  Avian retrovirus DNA internal attachment site requirements for full-site integration in vitro.

Authors:  R Chiu; D P Grandgenett
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

9.  Functional identification of nucleotides conferring substrate specificity to retroviral integrase reactions.

Authors:  M Balakrishnan; C B Jonsson
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

10.  In vitro HIV-1 selective integration into the target sequence and decoy-effect of the modified sequence.

Authors:  Tatsuaki Tsuruyama; Tonau Nakai; Takuya Hiratsuka; Guang Jin; Takuro Nakamura; Kenichi Yoshikawa
Journal:  PLoS One       Date:  2010-11-04       Impact factor: 3.240
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