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Literature DB >> 769677

Simple assay for 5-fluorocytosine in the presence of amphotericin B.

Abstract

A simple method for the measurement of 5-fluorocytosine in the presence of amphotericin B is described. The antifungal activity of amphotericin B is abolished by heating serum at 100 C for 45 min. 5-Fluorocytosine is unaffected by this treatment, and serum levels can be subsequently assayed by either tube dilution or disk diffusion methods.

Entities: Chemical

Mesh：

Substances：

Year: 1976 PMID： 769677 PMCID： PMC429539 DOI： 10.1128/AAC.9.3.381

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

10 in total

1. Therapy of cryptococcosis with a combination of flucytosine and amphotericin B.

Authors: J P Utz; I L Garriques; M A Sande; J F Warner; G L Mandell; R F McGehee; R J Duma; S Shadomy
Journal: J Infect Dis Date: 1975-10 Impact factor: 5.226

2. Rapid microbiological assay for 5-fluorocytosine.

Authors: D J Schiavone; M D Page; J K Dawborn
Journal: Br Med J Date: 1973-11-17

3. The kinetics of 5-fluorocytosine elimination in man.

Authors: D N Wade; G Sudlow
Journal: Aust N Z J Med Date: 1972-05

4. Torulopsis glabrata renal infection.

Authors: C A Kauffman; J S Tan
Journal: Am J Med Date: 1974-08 Impact factor: 4.965

5. A pharmacologic guide to the clinical use of amphotericin B.

Authors: D D Bindschadler; J E Bennett
Journal: J Infect Dis Date: 1969-10 Impact factor: 5.226

6. 5-fluorocytosine and urinary candidiasis.

Authors: R R Davies; D S Reeves
Journal: Br Med J Date: 1971-03-13

7. Candida endocarditis treated with 5-fluorocytosine.

Authors: C O Record; J M Skinner; P Sleight; D C Speller
Journal: Br Med J Date: 1971-01-30

8. Rapid, simple bioassay for 5-fluorocytosine in the presence of amphotericin B.

Authors: R L Kaspar; D J Drutz
Journal: Antimicrob Agents Chemother Date: 1975-04 Impact factor: 5.191

9. Pharmacological studies with 5-fluorocytosine.

Authors: E R Block; J E Bennett
Journal: Antimicrob Agents Chemother Date: 1972-06 Impact factor: 5.191

10. In vitro studies with 5-fluorocytosine.

Authors: S Shadomy
Journal: Appl Microbiol Date: 1969-06

10 in total

6 in total

Simple assay for 5-fluorocytosine in the presence of amphotericin B.

1. Therapy of cryptococcosis with a combination of flucytosine and amphotericin B.

2. Rapid microbiological assay for 5-fluorocytosine.

3. The kinetics of 5-fluorocytosine elimination in man.

4. Torulopsis glabrata renal infection.

5. A pharmacologic guide to the clinical use of amphotericin B.

6. 5-fluorocytosine and urinary candidiasis.

7. Candida endocarditis treated with 5-fluorocytosine.

8. Rapid, simple bioassay for 5-fluorocytosine in the presence of amphotericin B.

9. Pharmacological studies with 5-fluorocytosine.

10. In vitro studies with 5-fluorocytosine.

1. High-pressure liquid chromatographic assay of Bay n 7133 in human serum.

Review 2. Clinical pharmacokinetics of systemic antifungal drugs.

Review 3. Treatment of systemic fungal infections: recent progress and current problems.

4. Bone marrow toxicity associated with 5-fluorocytosine therapy.

5. Simplified bioassay method for measurement of flucytosine or ketoconazole.

6. Amphotericin B and 5-fluorocytosine: effects on cell-mediated immunity.