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Literature DB >> 5212581

Candida endocarditis treated with 5-fluorocytosine.

C O Record, J M Skinner, P Sleight, D C Speller.

Abstract

Three patients with endocarditis due to Candida species were treated with 5-fluorocytosine. One had endocarditis imposed on senile aortic sclerosis and survived and two had infections on prosthetic valves and died. In the latter two patients chemotherapy failed to eradicate the infection and was associated with marrow depression and possibly hepatic necrosis.

Entities: Chemical Disease Species

Mesh：

Substances：
Flucytosine

Year: 1971 PMID： 5212581 PMCID： PMC1794961 DOI： 10.1136/bmj.1.5743.262

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

10 in total

1. Cryptococcus neoformans infection of the central nervous system: a case treated by amphotericin B, with postmortem examination.

Authors: J M STEIN; P J BURDON
Journal: Ann Intern Med Date: 1960-02 Impact factor: 25.391

2. Fatal toxic reaction to amphotericin B in cryptococcal meningo-encephalitis.

Authors: B M CARNECCHIA; J F KURTZKE
Journal: Ann Intern Med Date: 1960-11 Impact factor: 25.391

3. Amphotericin B in treatment of disseminated moniliasis.

Authors: D B LOURIA; P DINEEN
Journal: JAMA Date: 1960-09-17 Impact factor: 56.272

4. Surgical treatment of candida endocarditis.

Authors: J H Kay; S Berstein; H K Tsuji; J V Redington; M Milgram; T Brem
Journal: JAMA Date: 1968-02-26 Impact factor: 56.272

5. Treatment of Candida sepsis and Cryptococcus meningitis with 5-fluorocytosine. A new antifungal agent.

Authors: D Tassel; M A Madoff
Journal: JAMA Date: 1968-10-21 Impact factor: 56.272

6. Candida endocarditis surrounding a Starr-Edwards prosthetic valve. Recovery of candida in hypertonic medium during treatment.

Authors: C Watanakunakorn; J Carleton; L M Goldberg; M Hamburger
Journal: Arch Intern Med Date: 1968-03

7. Candida endocarditis after heart surgery.

Authors: N Conway; M L Kothari; E Lockey; M H Yacoub
Journal: Thorax Date: 1968-07 Impact factor: 9.139

8. Serological evidence of Candida infection after open-heart surgery.

Authors: I G Murray; H R Buckley; G C Turner
Journal: J Med Microbiol Date: 1969-11-04 Impact factor: 2.472

9. Isolation of Candida protoplasts from a case of Candida endocarditis.

Authors: R Rosner
Journal: J Bacteriol Date: 1966-03 Impact factor: 3.490

10. In vitro studies with 5-fluorocytosine.

Authors: S Shadomy
Journal: Appl Microbiol Date: 1969-06

10 in total

20 in total

Candida endocarditis treated with 5-fluorocytosine.

1. Cryptococcus neoformans infection of the central nervous system: a case treated by amphotericin B, with postmortem examination.

2. Fatal toxic reaction to amphotericin B in cryptococcal meningo-encephalitis.

3. Amphotericin B in treatment of disseminated moniliasis.

4. Surgical treatment of candida endocarditis.

5. Treatment of Candida sepsis and Cryptococcus meningitis with 5-fluorocytosine. A new antifungal agent.

6. Candida endocarditis surrounding a Starr-Edwards prosthetic valve. Recovery of candida in hypertonic medium during treatment.

7. Candida endocarditis after heart surgery.

8. Serological evidence of Candida infection after open-heart surgery.

9. Isolation of Candida protoplasts from a case of Candida endocarditis.

10. In vitro studies with 5-fluorocytosine.

1. Editorial: Candida endocarditis.

2. Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine.

Review 3. Adverse drug reactions to systemic antifungals. Prevention and management.

4. Agranulocytosis and systemic candidiasis following clomipramine therapy.

Review 5. Fungal endocarditis: patients at risk and their treatment.

6. Use of 5-fluorocytosine in systemic candidiasis in infancy.

7. 5-fluorocytosine and urinary candidiasis.

8. Chemotherapeutic activity of 5-fluorocytosine and amphotericin B against Candida albicans in mice.

9. Pharmacological studies with 5-fluorocytosine.

10. Simple assay for 5-fluorocytosine in the presence of amphotericin B.