Literature DB >> 4584231

Rapid microbiological assay for 5-fluorocytosine.

D J Schiavone, M D Page, J K Dawborn.   

Abstract

A microbiological assay was developed for 5-fluorocytosine based on inhibition by the drug of the fall in pH produced by Candida albicans in a synthetic liquid culture medium. Serum and urine levels of the drug could be measured reproducibly in four hours.

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Year:  1973        PMID: 4584231      PMCID: PMC1587823          DOI: 10.1136/bmj.4.5889.380

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  4 in total

1.  Rapid microbiological assay of antibiotic in blood and other body fluids.

Authors:  S Faine; D C Knight
Journal:  Lancet       Date:  1968-08-17       Impact factor: 79.321

2.  The kinetics of 5-fluorocytosine elimination in man.

Authors:  D N Wade; G Sudlow
Journal:  Aust N Z J Med       Date:  1972-05

3.  In vitro studies with 5-fluorocytosine.

Authors:  S Shadomy
Journal:  Appl Microbiol       Date:  1969-06

4.  The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man.

Authors:  B A Koechlin; F Rubio; S Palmer; T Gabriel; R Duschinsky
Journal:  Biochem Pharmacol       Date:  1966-04       Impact factor: 5.858

  4 in total
  7 in total

Review 1.  Clinical pharmacokinetics of systemic antifungal drugs.

Authors:  T K Daneshmend; D W Warnock
Journal:  Clin Pharmacokinet       Date:  1983 Jan-Feb       Impact factor: 6.447

2.  High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells.

Authors:  A Newman-Tancredi; R Wootton; P G Strange
Journal:  Biochem J       Date:  1992-08-01       Impact factor: 3.857

3.  Simple assay for 5-fluorocytosine in the presence of amphotericin B.

Authors:  C A Kauffman; J A Carleton; P T Frame
Journal:  Antimicrob Agents Chemother       Date:  1976-03       Impact factor: 5.191

4.  Use of 5-fluorocytosine in patients with impaired renal function.

Authors:  J K Dawborn; M D Page; D J Schiavone
Journal:  Br Med J       Date:  1973-11-17

5.  Rapid microdilution-colorimetric assay for yeast susceptibility to fluorocytosine.

Authors:  B D Fisher; D Armstrong
Journal:  Antimicrob Agents Chemother       Date:  1977-11       Impact factor: 5.191

6.  Assay of flucytosine (5-fluorocytosine) in human plasma by high-pressure liquid chromatography.

Authors:  R W Bury; M L Mashford; H M Miles
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191

7.  Analysis of pH and buffer effects on flucytosine activity in broth dilution susceptibility testing of Candida albicans in two synthetic media.

Authors:  D L Calhoun; J N Galgiani
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

  7 in total

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