Literature DB >> 7692729

Hepatocyte paraffin 1: a monoclonal antibody that reacts with hepatocytes and can be used for differential diagnosis of hepatic tumors.

A E Wennerberg1, M A Nalesnik, W B Coleman.   

Abstract

Hepatocyte paraffin 1 is a monoclonal antibody that has been developed specifically to react with hepatocytes in routine formalin-fixed and paraffin-embedded surgical pathology tissues. It results in a distinct, granular cytoplasmic staining of hepatocytes but fails to react with bile ducts and nonparenchymal liver cells. The antibody decorates a majority of hepatocellular carcinomas, including fibrolamellar variants. It fails to react with a wide variety of other adult malignancies, with the exception of focal staining in a few gastrointestinal malignancies, including a subpopulation of gastric carcinomas.

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Year:  1993        PMID: 7692729      PMCID: PMC1887067     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN: 0002-9440            Impact factor:   4.307


  8 in total

1.  A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines.

Authors:  J F Kearney; A Radbruch; B Liesegang; K Rajewsky
Journal:  J Immunol       Date:  1979-10       Impact factor: 5.422

2.  Continuous cultures of fused cells secreting antibody of predefined specificity.

Authors:  G Köhler; C Milstein
Journal:  Nature       Date:  1975-08-07       Impact factor: 49.962

Review 3.  Alpha-fetoprotein: reevaluation in hepatology.

Authors:  K Taketa
Journal:  Hepatology       Date:  1990-12       Impact factor: 17.425

Review 4.  Immunohistochemistry of solid tumors. Brief review of selected problems.

Authors:  M Miettinen
Journal:  APMIS       Date:  1990-03       Impact factor: 3.205

5.  Characterization of a monoclonal anti-idiotype antibody to human anti-factor VIII antibodies.

Authors:  B C Lubahn; H M Reisner
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

6.  Use of monoclonal antibodies in an enzyme immunoassay for factor VIII-related antigen.

Authors:  L A Bradley; E L Franco; H M Reisner
Journal:  Clin Chem       Date:  1984-01       Impact factor: 8.327

7.  Immunocytochemical staining of fine-needle aspiration biopsies of the liver as a diagnostic tool for hepatocellular carcinoma.

Authors:  D E Johnson; C N Powers; G Rupp; W J Frable
Journal:  Mod Pathol       Date:  1992-03       Impact factor: 7.842

8.  Hepatocellular carcinoma, adenoma, and focal nodular hyperplasia. Comparative histopathologic study with immunohistochemical parameters.

Authors:  I A Koelma; M Nap; S Huitema; R A Krom; H J Houthoff
Journal:  Arch Pathol Lab Med       Date:  1986-11       Impact factor: 5.534

  8 in total
  33 in total

Review 1.  Ectopic livers and related pathology: report of three cases of benign lesions.

Authors:  Nicola Leone; Silvia Saettone; Paolo De Paolis; Patrizia Carucci; Franco Brunello; Claudio De Angelis; Guido Menozzi; Mario Rizzetto
Journal:  Dig Dis Sci       Date:  2005-10       Impact factor: 3.199

2.  Real time monitoring of radiofrequency ablation based on MR thermometry and thermal dose in the pig liver in vivo.

Authors:  Olivier Seror; Matthieu Lepetit-Coiffé; Brigitte Le Bail; Baudouin Denis de Senneville; Hervé Trillaud; Chrit Moonen; Bruno Quesson
Journal:  Eur Radiol       Date:  2007-09-26       Impact factor: 5.315

3.  Utility of FNAC in Conjunction with Cell Block for Diagnosing Space-Occupying Lesion (SOL) of Liver with Emphasis on Differentiating Hepatocellular Carcinoma from Metastatic SOL: Analysis of 61 Cases.

Authors:  Haq Sheefa; Jadhav Lata; Mubeen Basharat; Makhdoomi Rumana; Malhotra Veena
Journal:  Oman Med J       Date:  2016-03

4.  Adenoendocrine cell carcinoma of the gallbladder producing a high level of alpha-fetoprotein.

Authors:  Hideki Fujii; Kanji Yamaguchi; Naoki Ohnishi; Masafumi Sakamoto; Tohru Ohkawara; Yoshihiko Sawa; Koichi Nishida; Yasuo Ohkawara; Yoshinori Harada; Hideo Tanaka; Tetsuro Takamatsu; Yoshito Itoh
Journal:  Clin J Gastroenterol       Date:  2012-06-07

5.  The Applicability of a Human Immunohistochemical Panel to Mouse Models of Hepatocellular Neoplasia.

Authors:  Kenneth J Salleng; Frank L Revetta; Natasha G Deane; M Kay Washington
Journal:  Comp Med       Date:  2015-10       Impact factor: 0.982

6.  A case of ectopic hepatocellular carcinoma in the jejunum.

Authors:  Masato Shigemori; Masahiko Kondo; Hidemasa Azechi; Fumihiko Inoue; Jun Tamura; Hisato Kobayashi; Tatsuyoshi Saiga
Journal:  J Gastroenterol       Date:  2006-09       Impact factor: 7.527

7.  Role of Hepatocyte Paraffin 1 antigen in the course of colorectal carcinogenesis.

Authors:  Riham M Abu-Zeid; Rola M Farid
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2013-09-10

8.  Overexpression of CPS1 is an independent negative prognosticator in rectal cancers receiving concurrent chemoradiotherapy.

Authors:  Yi-Ying Lee; Chien-Feng Li; Ching-Yih Lin; Sung-Wei Lee; Ming-Jen Sheu; Li-Ching Lin; Tzu-Ju Chen; Ting-Feng Wu; Chung-Hsi Hsing
Journal:  Tumour Biol       Date:  2014-08-07

9.  Intramucosal stomach adenocarcinoma metastasizing as a large intraabdominal mass with focal choriocarcinomatous differentiation.

Authors:  Yukio Fujiyoshi; Shuying Jiang; Xia Feng
Journal:  Int J Clin Exp Pathol       Date:  2012-10-01

10.  Hepatoid adenocarcinoma of the stomach with liver metastasis mimicking hepatocellular carcinoma: a case report.

Authors:  Chih-Wen Lin; Chia-Chang Hsu; Hong-Cheng Chang; Yu-Chiun Sun; Po-Lin Sun; Chuan-Yan Hsu; Daw-Shyong Perng
Journal:  Cases J       Date:  2009-08-11
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