Literature DB >> 7683203

Audit: the use of radiotherapy for NSCLC in the UK.

E J Maher1, A Timothy, C J Squire, A Goodman, S J Karp, C H Paine, R Ryall, G Read.   

Abstract

A questionnaire on the management of NSCLC was sent to all clinical oncologists in the UK. Responses were received from 121 individuals with at least one representative response from each of 54 British radiotherapy units. Results were then discussed at an open meeting attended by a cross section of clinical oncologists; a synopsis of responses to the questionnaire and discussion at this meeting is contained in this report. A majority of respondents estimated treatment of NSCLC to make up 10%-25% of their work-load. Radical and palliative treatments could be clearly distinguished, and aims of treatment, selection criteria and radiotherapy schedules were consistent with recommendations in the published literature. More than 90% of treatments were with palliative rather than radical intent. Radical treatment schedules could be divided according to dose (< 50 Gy, 50-55 Gy and >55 Gy), number of fractions (< 20, 20, > 20 fractions), overall time < 4/52, 4/52, > 4/52), dose per fraction (> 2.75 Gy, 2.1-2.75 Gy, < or = 2 Gy) and target volume (tumour alone, tumour and hilar nodes, or tumour, hilar and mediastinal nodes). Divided thus, radical techniques fell into three broad groups, each of the three techniques supported by a body of literature. Choice of schedule could be related to a heterogeneous referral pattern and unresolved controversies, identified as debate on the value of treating mediastinal lymphadenopathy with high dose radiation, the value of 'subradical doses' of radiation for microscopic disease, and the relative importance of volume treated, total dose, dose per fraction and overall treatment time in achieving an optimal therapeutic ratio.(ABSTRACT TRUNCATED AT 250 WORDS)

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Year:  1993        PMID: 7683203     DOI: 10.1016/s0936-6555(05)80850-7

Source DB:  PubMed          Journal:  Clin Oncol (R Coll Radiol)        ISSN: 0936-6555            Impact factor:   4.126


  5 in total

1.  Managing patients with lung cancer. New guidelines should improve standards of care.

Authors:  P Simmonds
Journal:  BMJ       Date:  1999-08-28

Review 2.  Management of lung cancer.

Authors:  M F Muers; R A Haward
Journal:  Thorax       Date:  1996-06       Impact factor: 9.139

Review 3.  Palliative radiotherapy regimens for patients with thoracic symptoms from non-small cell lung cancer.

Authors:  Rosemary Stevens; Fergus Macbeth; Elizabeth Toy; Bernadette Coles; Jason F Lester
Journal:  Cochrane Database Syst Rev       Date:  2015-01-14

4.  Management and survival of patients with lung cancer in Scotland diagnosed in 1995: results of a national population based study.

Authors:  A Gregor; C S Thomson; D H Brewster; P L Stroner; J Davidson; R J Fergusson; R Milroy
Journal:  Thorax       Date:  2001-03       Impact factor: 9.139

5.  Radiobiological prediction of normal tissue toxicities and tumour response in the radiotherapy of advanced non-small-cell lung cancer.

Authors:  J M Singer; P Price; R G Dale
Journal:  Br J Cancer       Date:  1998-12       Impact factor: 7.640

  5 in total

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