Literature DB >> 7678907

Stratification of rodent carcinogenicity bioassay results to reflect relative human hazard.

R W Tennant1.   

Abstract

Trans-species, multiple site (particularly common site between species), mutagenic rodent carcinogens are less affected by the influences of polymorphic genes than are chemicals inducing more limited carcinogenic effects. Trans-species carcinogens, therefore, should represent a first priority for attention for human health risk.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 7678907     DOI： 10.1016/0027-5107(93)90006-2

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  13 in total

Review 1.  Evaluation of in vitro assays for assessing the toxicity of cigarette smoke and smokeless tobacco.

Authors:  Michael D Johnson; Jodi Schilz; Mirjana V Djordjevic; Jerry R Rice; Peter G Shields
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2009-12       Impact factor: 4.254

Review 2.  The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century.

Authors:  Larry D Claxton; Gisela de A Umbuzeiro; David M DeMarini
Journal:  Environ Health Perspect       Date:  2010-11       Impact factor: 9.031

Review 3.  The role of transgenic mouse models in carcinogen identification.

Authors:  John B Pritchard; John E French; Barbara J Davis; Joseph K Haseman
Journal:  Environ Health Perspect       Date:  2003-04       Impact factor: 9.031

Review 4.  The traditional toxicologic paradigm is correct: dose influences mechanism.

Authors:  J I Goodman
Journal:  Environ Health Perspect       Date:  1998-02       Impact factor: 9.031

Review 5.  In vivo transgenic bioassays and assessment of the carcinogenic potential of pharmaceuticals.

Authors:  J F Contrera; J J DeGeorge
Journal:  Environ Health Perspect       Date:  1998-02       Impact factor: 9.031

6.  Evaluation and validation issues in the development of transgenic mouse carcinogenicity bioassays.

Authors:  R W Tennant
Journal:  Environ Health Perspect       Date:  1998-04       Impact factor: 9.031

Review 7.  Use of a multistrain assay could improve the NTP carcinogenesis bioassay.

Authors:  M F Festing
Journal:  Environ Health Perspect       Date:  1995-01       Impact factor: 9.031

8.  Predictions for the outcome of rodent carcinogenicity bioassays: identification of trans-species carcinogens and noncarcinogens.

Authors:  R W Tennant; J Spalding
Journal:  Environ Health Perspect       Date:  1996-10       Impact factor: 9.031

9.  The carcinogenesis bioassay in perspective: application in identifying human cancer hazards.

Authors:  V A Fung; J C Barrett; J Huff
Journal:  Environ Health Perspect       Date:  1995 Jul-Aug       Impact factor: 9.031

10.  Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models.

Authors:  R W Tennant; J E French; J W Spalding
Journal:  Environ Health Perspect       Date:  1995-10       Impact factor: 9.031
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.