Literature DB >> 7665674

The DNA-binding protein pUL57 of human cytomegalovirus is a major target antigen for the immunoglobulin M antibody response during acute infection.

R Vornhagen1, W Hinderer, H H Sonneborn, G Bein, L Matter, T H The, G Jahn, B Plachter.   

Abstract

A small polypeptide from pUL57 of human cytomegalovirus was identified as a major target for the immunoglobulin M antibody response. This antigen seems to be superior to antigenic fragments from pp150 and p52 in the identification of sera from acutely infected patients. It may therefore represent an essential antigen for recombinant immunoglobulin M antibody tests for human cytomegalovirus.

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Year:  1995        PMID： 7665674      PMCID： PMC228303          DOI： 10.1128/jcm.33.7.1927-1930.1995

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  13 in total

1.  Large-scale screening of human sera with cytomegalovirus recombinant antigens.

Authors:  M P Landini; M X Guan; G Jahn; W Lindenmaier; M Mach; A Ripalti; A Necker; T Lazzarotto; B Plachter
Journal:  J Clin Microbiol       Date:  1990-06       Impact factor: 5.948

2.  Serodiagnosis of infectious mononucleosis by using recombinant Epstein-Barr virus antigens and enzyme-linked immunosorbent assay technology.

Authors:  M Gorgievski-Hrisoho; W Hinderer; H Nebel-Schickel; J Horn; R Vornhagen; H H Sonneborn; H Wolf; G Siegl
Journal:  J Clin Microbiol       Date:  1990-10       Impact factor: 5.948

Review 3.  Cytomegalovirus antigenemia.

Authors:  T H The; W van der Bij; A P van den Berg; M van der Giessen; J Weits; H G Sprenger; W J van Son
Journal:  Rev Infect Dis       Date:  1990 Sep-Oct

Review 4.  Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.

Authors:  M S Chee; A T Bankier; S Beck; R Bohni; C M Brown; R Cerny; T Horsnell; C A Hutchison; T Kouzarides; J A Martignetti
Journal:  Curr Top Microbiol Immunol       Date:  1990       Impact factor: 4.291

5.  Quantitative measurement of cytomegalovirus-specific IgG and IgM antibodies in relation to cytomegalovirus antigenaemia and disease activity in kidney recipients with an active cytomegalovirus infection.

Authors:  M Van der Giessen; A P van den Berg; W van der Bij; S Postma; W J van Son; T H The
Journal:  Clin Exp Immunol       Date:  1990-04       Impact factor: 4.330

6.  Expression of the Epstein-Barr virus 138-kDa early protein in Escherichia coli for the use as antigen in diagnostic tests.

Authors:  M Motz; J Fan; R Seibl; W Jilg; H Wolf
Journal:  Gene       Date:  1986       Impact factor: 3.688

7.  Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase.

Authors:  D B Smith; K S Johnson
Journal:  Gene       Date:  1988-07-15       Impact factor: 3.688

Review 8.  Management of cytomegalovirus disease with antiviral drugs.

Authors:  H H Balfour
Journal:  Rev Infect Dis       Date:  1990 Sep-Oct

9.  Structural organization of the conserved gene block of Herpesvirus saimiri coding for DNA polymerase, glycoprotein B, and major DNA binding protein.

Authors:  J C Albrecht; B Fleckenstein
Journal:  Virology       Date:  1990-02       Impact factor: 3.616

10.  Early serodiagnosis of acute human cytomegalovirus infection by enzyme-linked immunosorbent assay using recombinant antigens.

Authors:  R Vornhagen; B Plachter; W Hinderer; T H The; J Van Zanten; L Matter; C A Schmidt; H H Sonneborn; G Jahn
Journal:  J Clin Microbiol       Date:  1994-04       Impact factor: 5.948
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  11 in total

1.  Search for cytomegalovirus-specific immunoglobulin M: comparison between a new western blot, conventional western blot, and nine commercially available assays.

Authors:  T Lazzarotto; S Brojanac; G T Maine; M P Landini
Journal:  Clin Diagn Lab Immunol       Date:  1997-07

2.  Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase.

Authors:  H S Hiemstra; N C Schloot; P A van Veelen; S J Willemen; K L Franken; J J van Rood; R R de Vries; A Chaudhuri; P O Behan; J W Drijfhout; B O Roep
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-27       Impact factor: 11.205

3.  Immunoglobulin A-specific serodiagnosis of acute human cytomegalovirus infection by using recombinant viral antigens.

Authors:  R Vornhagen; W Hinderer; H H Sonneborn; G Bein; L Matter; T H The; G Jahn; B Plachter
Journal:  J Clin Microbiol       Date:  1996-04       Impact factor: 5.948

4.  The DNA-binding protein pUL57 of human cytomegalovirus: comparison of specific immunoglobulin M (IgM) reactivity with IgM reactivity to other major target antigens.

Authors:  G T Maine; T Lazzarotto; L E Chovan; R Flanders; M P Landini
Journal:  Clin Diagn Lab Immunol       Date:  1996-05

5.  A novel Western blot test containing both viral and recombinant proteins for anticytomegalovirus immunoglobulin M detection.

Authors:  T Lazzarotto; G T Maine; P Dal Monte; A Ripalti; M P Landini
Journal:  J Clin Microbiol       Date:  1997-02       Impact factor: 5.948

6.  Development and clinical evaluation of a recombinant-antigen-based cytomegalovirus immunoglobulin M automated immunoassay using the Abbott AxSYM analyzer.

Authors:  G T Maine; R Stricker; M Schuler; J Spesard; S Brojanac; B Iriarte; K Herwig; T Gramins; B Combs; J Wise; H Simmons; T Gram; J Lonze; D Ruzicki; B Byrne; J D Clifton; L E Chovan; D Wachta; C Holas; D Wang; T Wilson; S Tomazic-Allen; M A Clements; G L Wright; T Lazzarotto; A Ripalti; M P Landini
Journal:  J Clin Microbiol       Date:  2000-04       Impact factor: 5.948

7.  Cross-reactivity of Epstein-Barr virus-specific immunoglobulin M antibodies with cytomegalovirus antigens containing glycine homopolymers.

Authors:  D Lang; R Vornhagen; M Rothe; W Hinderer; H H Sonneborn; B Plachter
Journal:  Clin Diagn Lab Immunol       Date:  2001-07

8.  Reactivity to p52 and CM2 recombinant proteins in primary human cytomegalovirus infection with a microparticle agglutination assay.

Authors:  E Nulens; M Bodéus; F Bonelli; A Soleti; P Goubau
Journal:  Clin Diagn Lab Immunol       Date:  2000-07

Review 9.  Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant.

Authors:  Maria Grazia Revello; Giuseppe Gerna
Journal:  Clin Microbiol Rev       Date:  2002-10       Impact factor: 26.132

10.  Development of a new cytomegalovirus (CMV) immunoglobulin M (IgM) immunoblot for detection of CMV-specific IgM.

Authors:  T Lazzarotto; A Ripalti; G Bergamini; M C Battista; P Spezzacatena; F Campanini; P Pradelli; S Varani; L Gabrielli; G T Maine; M P Landini
Journal:  J Clin Microbiol       Date:  1998-11       Impact factor: 5.948
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