| Literature DB >> 7637779 |
Abstract
Clusters of homeotic genes sculpt the morphology of animal body plans and body parts. Different body patterns may evolve through changes in homeotic gene number, regulation or function. Recent evidence suggests that homeotic gene clusters were duplicated early in vertebrate evolution, but the generation of arthropod and tetrapod diversity has largely involved regulatory changes in the expression of conserved arrays of homeotic genes and the evolution of interactions between homeotic proteins and the genes they regulate.Mesh:
Year: 1995 PMID: 7637779 DOI: 10.1038/376479a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962