Literature DB >> 7619678

Effects of treatment with simvastatin and pravastatin on cognitive function in patients with hypercholesterolaemia.

N Cutler1, J Sramek, A Veroff, G Block, L Stauffer, C Lines.   

Abstract

The effects of equi-efficacious doses of the cholesterol-lowering drugs simvastatin (20 mg day-1) and pravastatin (40 mg day-1) on tests of cognitive function were investigated in a double-blind, placebo-controlled, 2-period (4 weeks per period), incomplete block, crossover study of 36 patients (24 per treatment) with hypercholesterolaemia. After 4 weeks neither of the active treatments differed significantly from placebo on any cognitive measure.

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Year:  1995        PMID： 7619678      PMCID： PMC1365013          DOI： 10.1111/j.1365-2125.1995.tb04458.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  10 in total

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  10 in total

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