Literature DB >> 7609088

Suppression of simian immunodeficiency virus replication by human immunodeficiency virus type 1 trans-dominant negative rev mutants.

C L Endres1, E P Bergquam, M K Axthelm, S W Wong.   

Abstract

We demonstrate that trans-dominant negative rev mutants are able to suppress simian immunodeficiency virus provirus replication in both transient cotransfection assays and stably transduced HUT 78 cells. These studies suggest that the efficacy of trans-dominant rev strategies in reducing viral burden may be evaluated in a simian immunodeficiency virus-rhesus macaque animal model.

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Year:  1995        PMID： 7609088      PMCID： PMC189339          DOI： 10.1128/JVI.69.8.5164-5166.1995

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  21 in total

1.  Improved retroviral vectors for gene transfer and expression.

Authors:  A D Miller; G J Rosman
Journal:  Biotechniques       Date:  1989-10       Impact factor: 1.993

2.  Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus.

Authors:  H Kestler; T Kodama; D Ringler; M Marthas; N Pedersen; A Lackner; D Regier; P Sehgal; M Daniel; N King
Journal:  Science       Date:  1990-06-01       Impact factor: 47.728

Review 3.  Simian immunodeficiency viruses.

Authors:  R C Desrosiers
Journal:  Annu Rev Microbiol       Date:  1988       Impact factor: 15.500

4.  Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function.

Authors:  M H Malim; S Böhnlein; J Hauber; B R Cullen
Journal:  Cell       Date:  1989-07-14       Impact factor: 41.582

5.  Gene therapy. Intracellular immunization.

Authors:  D Baltimore
Journal:  Nature       Date:  1988-09-29       Impact factor: 49.962

6.  Use of eukaryotic expression technology in the functional analysis of cloned genes.

Authors:  B R Cullen
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

7.  Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Rev-binding domain.

Authors:  S W Lee; H F Gallardo; E Gilboa; C Smith
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

8.  Characterization of the AIDS-associated retrovirus reverse transcriptase and optimal conditions for its detection in virions.

Authors:  A D Hoffman; B Banapour; J A Levy
Journal:  Virology       Date:  1985-12       Impact factor: 3.616

9.  Expression of the neomycin-resistance (neo) gene induces alterations in gene expression and metabolism.

Authors:  A Valera; J C Perales; M Hatzoglou; F Bosch
Journal:  Hum Gene Ther       Date:  1994-04       Impact factor: 5.695

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162
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  3 in total

1.  A rhesus macaque rhadinovirus related to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 encodes a functional homologue of interleukin-6.

Authors:  J A Kaleeba; E P Bergquam; S W Wong
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

2.  Nuclear transport of human immunodeficiency virus type 1, visna virus, and equine infectious anemia virus Rev proteins: identification of a family of transferable nuclear export signals.

Authors:  B E Meyer; J L Meinkoth; M H Malim
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103

3.  A therapeutic SIV DNA vaccine elicits T-cell immune responses, but no sustained control of viremia in SIVmac239-infected rhesus macaques.

Authors:  Jan zur Megede; Brigitte Sanders-Beer; Peter Silvera; Dawn Golightly; Abigail Bowlsbey; Diane Hebblewaite; Deborah Sites; Lourdes Nieves-Duran; Ranjana Srivastava; Gillis R Otten; Dietmar Rabussay; Lei Zhang; Jeffrey B Ulmer; Susan W Barnett; John J Donnelly
Journal:  AIDS Res Hum Retroviruses       Date:  2008-08       Impact factor: 2.205
  3 in total

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