Literature DB >> 7608890

Further evidence supporting the importance of and the restrictions on a carbon-centered radical for high antimalarial activity of 1,2,4-trioxanes like artemisinin.

G H Posner1, D Wang, J N Cumming, C H Oh, A N French, A L Bodley, T A Shapiro.   

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Year:  1995        PMID: 7608890     DOI: 10.1021/jm00013a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  16 in total

1.  Comparative molecular field analysis of artemisinin derivatives: ab initio versus semiempirical optimized structures.

Authors:  S Tonmunphean; S Kokpol; V Parasuk; P Wolschann; R H Winger; K R Liedl; B M Rode
Journal:  J Comput Aided Mol Des       Date:  1998-07       Impact factor: 3.686

2.  Determination of artemisinin in Artemisia sieberi and anticoccidial effects of the plant extract in broiler chickens.

Authors:  H A Arab; S Rahbari; A Rassouli; M H Moslemi; F Khosravirad
Journal:  Trop Anim Health Prod       Date:  2006       Impact factor: 1.559

3.  Antiplasmodial activity of two medicinal plants against clinical isolates of Plasmodium falciparum and Plasmodium berghei infected mice.

Authors:  Serge David Dago Attemene; Sylvain Beourou; Karim Tuo; Albert Alloh Gnondjui; Abibatou Konate; Andre Offianan Toure; Seraphin Kati-Coulibaly; Joseph Alico Djaman
Journal:  J Parasit Dis       Date:  2017-11-10

Review 4.  Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy.

Authors:  S R Meshnick; T E Taylor; S Kamchonwongpaisan
Journal:  Microbiol Rev       Date:  1996-06

5.  A study on antimalarial artemisinin derivatives using MEP maps and multivariate QSAR.

Authors:  Fábio José B Cardoso; Antonio Florêncio de Figueiredo; Maycon da Silva Lobato; Ricardo Moraes de Miranda; Ruth Catarine O de Almeida; José Ciríaco Pinheiro
Journal:  J Mol Model       Date:  2007-10-30       Impact factor: 1.810

6.  Artemisinin and a series of novel endoperoxide antimalarials exert early effects on digestive vacuole morphology.

Authors:  Maria del Pilar Crespo; Thomas D Avery; Eric Hanssen; Emma Fox; Tony V Robinson; Peter Valente; Dennis K Taylor; Leann Tilley
Journal:  Antimicrob Agents Chemother       Date:  2007-10-15       Impact factor: 5.191

7.  Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential.

Authors:  Thomas Antoine; Nicholas Fisher; Richard Amewu; Paul M O'Neill; Stephen A Ward; Giancarlo A Biagini
Journal:  J Antimicrob Chemother       Date:  2013-12-12       Impact factor: 5.790

8.  A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.

Authors:  Hanafy M Ismail; Victoria E Barton; Matthew Panchana; Sitthivut Charoensutthivarakul; Giancarlo A Biagini; Stephen A Ward; Paul M O'Neill
Journal:  Angew Chem Int Ed Engl       Date:  2016-04-18       Impact factor: 15.336

9.  A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.

Authors:  Hanafy M Ismail; Victoria E Barton; Matthew Panchana; Sitthivut Charoensutthivarakul; Giancarlo A Biagini; Stephen A Ward; Paul M O'Neill
Journal:  Angew Chem Weinheim Bergstr Ger       Date:  2016-04-18

10.  A plausible mechanism for the antimalarial activity of artemisinin: A computational approach.

Authors:  Ashutosh Shandilya; Sajeev Chacko; B Jayaram; Indira Ghosh
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379

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