| Literature DB >> 75832 |
Abstract
Besides the AT-specific fluorochromes, GC-specific fluorescent antibiotics are now available for chromosomal analysis. Chromosomal bands represent large accumulation of DNA sequences with similar AT:GC ratio. These uniform differences from the mean AT:GC ratio in the bands can be explained only by at least partial repetition of short DNA sequences in these regions. By comparison of various staining techniques more information also on the constitutive heterochromatin in man becomes available. The human NOR region exhibits a complex organization when studied by various base-specific fluorochromes and silver staining. The DNA-specific fluorochromes are also useful tools in cytophotometric DNA measurements.Entities:
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Year: 1978 PMID: 75832 DOI: 10.1007/BF00278866
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132