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Literature DB >> 6162775

On the structure and polymorphism of the human chromosome no. 15.

Abstract

Chromosome preparations from 67 randomly selected healthy individuals were consecutively stained with silver, mithramycin, pentamidine-DAPI, and quinacrine mustard. In the short arm of the chromosome 15 up to six regions, which were highly polymorphic, apparently independently of each other, could be detected by the given methods. The frequency of occurrence of each individual polymorphic feature in the population investigated ranges from 70% to 87%. They appear randomly and independently of each other.

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Year: 1980 PMID： 6162775 DOI： 10.1007/BF00281580

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

22 in total

1. Size variation polymorphisms of the short arm of human acrocentric chrosomes determined by R-banding by fluorescence using acridine orange (RFA).

Authors: R S Verma; H Dosik; H A Lubs
Journal: Hum Genet Date: 1977-09-22 Impact factor: 4.132

On the structure and polymorphism of the human chromosome no. 15.

1. Size variation polymorphisms of the short arm of human acrocentric chrosomes determined by R-banding by fluorescence using acridine orange (RFA).

Review 2. Functional aspects of satellite DNA and heterochromatin.

Review 3. Human chromosomal heteromorphisms: nature and clinical significance.

4. G-banding patterns of high-resolution human chromosomes 6--22, X, and Y.

5. An improved technique for selective silver staining of nucleolar organizer regions in human chromosomes.

6. [Polymorphisms of the human chromosome no. 15 (author's transl)].

7. Sequential Q- and Acridine orange-marker technique.

8. Quinacrine, a chromosome stain specific for deoxyadenylate-deoxythymidylaterich regions in DNA.

9. Effects of counterstaining with DNA binding drugs on fluorescent banding patterns of human and mammalian chromosomes.

Review 10. Structure and variability of human chromosomes analyzed by recent techniques.

1. Intensity heteromorphisms of human chromosome 15p by DA/DAPI technique.

Review 2. Aspects of evaluation, significance, and evolution of human C-band heteromorphism.

3. Polymorphism of 5-methylcytosine-rich DNA in human acrocentric chromosomes.

4. Preferential fluorescent staining of heterochromatic regions in human chromosomes 9, 15, and the Y by D 287/170.

5. Investigation of human chromosome polymorphisms by scanning electron microscopy.

6. Parental origin of chromosome 15 deletion in Prader-Willi syndrome.