Literature DB >> 7579887

Genetic map of 16 polymorphic markers forming three linkage groups assigned to rat chromosome 4.

E A Goldmuntz1, E F Remmers, Y Du, H Zha, P Mathern, L J Crofford, R L Wilder.   

Abstract

Sixteen polymorphic markers, including markers for eight new loci, forming three linkage groups, were assigned to rat Chromosome (Chr) 4 by linkage analysis of the progeny of an F2 intercross of Fischer (F344/N) and Lewis (LEW/N) inbred rats. One gene, Igk, was mapped by restriction fragment length polymorphism (RFLP) analysis. One marker for Tcrb was identified by the polymorphic insertion of a repetitive LINE element. The remaining 14 markers contained polymorphic simple sequence repeats (SSRs). Ten were identified in genes (Tgfa, Npy, Prss1, Prss2, Aldr1, Iapp, Prp, Eno2, Cacnl1a1, and Il6), one was identified in a sequence related to a gene (Egr4l1), and three were identified in anonymous DNA segments. The SSR markers were highly polymorphic in 16 inbred rat strains. These markers expand the genetic map of the rat and should be useful in future genetic studies of inbred rats.

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Year:  1995        PMID： 7579887     DOI： 10.1007/BF00360654

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  12 in total

1.  Computerized estimation of size of nucleic acid fragments using the four-parameter logistic model.

Authors:  K E Oerter; P J Munson; W O McBride; D Rodbard
Journal:  Anal Biochem       Date:  1990-09       Impact factor: 3.365

2.  Linkage map of 10 polymorphic markers on rat chromosome 2.

Authors:  H Zha; R L Wilder; E A Goldmuntz; J M Cash; L J Crofford; P Mathern; E F Remmers
Journal:  Cytogenet Cell Genet       Date:  1993

3.  A genetic linkage map of the laboratory rat, Rattus norvegicus.

Authors:  H J Jacob; D M Brown; R K Bunker; M J Daly; V J Dzau; A Goodman; G Koike; V Kren; T Kurtz; A Lernmark
Journal:  Nat Genet       Date:  1995-01       Impact factor: 38.330

4.  Genetic map of nine polymorphic loci comprising a single linkage group on rat chromosome 10: evidence for linkage conservation with human chromosome 17 and mouse chromosome 11.

Authors:  E F Remmers; E A Goldmuntz; J M Cash; L J Crofford; B Misiewicz-Poltorak; H Zha; R L Wilder
Journal:  Genomics       Date:  1992-11       Impact factor: 5.736

5.  Linkage map of seven polymorphic markers on rat chromosome 18.

Authors:  E F Remmers; E A Goldmuntz; H Zha; L J Crofford; J M Cash; P Mathern; Y Du; R L Wilder
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

6.  Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.

Authors:  P Hilbert; K Lindpaintner; J S Beckmann; T Serikawa; F Soubrier; C Dubay; P Cartwright; B De Gouyon; C Julier; S Takahasi
Journal:  Nature       Date:  1991-10-10       Impact factor: 49.962

7.  Alleles of the rat T-cell receptor beta chain gene complex.

Authors:  E P Blankenhorn; P D Smith; C B Williams; G A Gutman
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

8.  MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.

Authors:  E S Lander; P Green; J Abrahamson; A Barlow; M J Daly; S E Lincoln; L A Newberg; L Newburg
Journal:  Genomics       Date:  1987-10       Impact factor: 5.736

9.  Genetic map of seven polymorphic markers comprising a single linkage group on rat chromosome 5.

Authors:  E A Goldmuntz; E F Remmers; H Zha; P Mathern; Y Du; L J Crofford; R L Wilder
Journal:  Mamm Genome       Date:  1993-11       Impact factor: 2.957

10.  A rat genetic linkage map and comparative maps for mouse or human homologous rat genes.

Authors:  J Yamada; T Kuramoto; T Serikawa
Journal:  Mamm Genome       Date:  1994-02       Impact factor: 2.957
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