Literature DB >> 7549630

Incidence of cancer among Finnish airline cabin attendants, 1967-92.

E Pukkala1, A Auvinen, G Wahlberg.   

Abstract

OBJECTIVE: To assess whether occupational exposure among commercial airline cabin attendants are associated with risk of cancer.
DESIGN: Record linkage study.
SETTING: Finland. SUBJECTS-1577 female and 187 male cabin attendants who had worked for the Finnish airline companies. MAIN OUTCOME MEASURE: Standardised incidence ratio; expected number of cases based on national cancer incidences.
RESULTS: A significant excess of breast cancer (standardised incidence ratio 1.87 (95% confidence interval 1.15 to 2.23)) and bone cancer (15.10 (1.82 to 54.40)) was found among female workers. The risk of breast cancer was most prominent 15 years after recruitment. Risks of leukaemia (3.57 (0.43 to 12.9)) and skin melanoma (2.11 (0.43 to 6.15) were not significantly raised. Among men, one lymphoma and one Kaposi's sarcoma were found (expected number of cases 1.6).
CONCLUSIONS: Although the lifestyle of cabin attendants is different from that of the reference population--for example, in terms of social status and parity--concentration of the excess risks to primary sites sensitive to radiation suggests that ionising radiation during flights may add to the cancer risk of all flight personnel. Otherwise the lifestyle of cabin attendants did not seem to affect their risks of cancer. Estimates of the effect of reproductive risk factors only partly explained the increased risk of breast cancer. If present estimates of health hazards due to radiation are also valid for cosmic radiation, then the radiation doses of cabin attendants seem too small to account entirely for the observed excess risk.

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Year:  1995        PMID: 7549630      PMCID: PMC2551425          DOI: 10.1136/bmj.311.7006.649

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  6 in total

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Authors:  K O'Brien; J E McLaughlin
Journal:  Health Phys       Date:  1972-03       Impact factor: 1.316

2.  Galactic cosmic radiation exposure and associated health risks for air carrier crewmembers.

Authors:  W Friedberg; D N Faulkner; L Snyder; E B Darden; K O'Brien
Journal:  Aviat Space Environ Med       Date:  1989-11

3.  Age at first birth, parity and risk of breast cancer: a meta-analysis of 8 studies from the Nordic countries.

Authors:  M Ewertz; S W Duffy; H O Adami; G Kvåle; E Lund; O Meirik; A Mellemgaard; I Soini; H Tulinius
Journal:  Int J Cancer       Date:  1990-10-15       Impact factor: 7.396

4.  Mortality and cancer incidence in a cohort of commercial airline pilots.

Authors:  P R Band; J J Spinelli; V T Ng; J Moody; R P Gallagher
Journal:  Aviat Space Environ Med       Date:  1990-04

5.  Data quality and quality control of a population-based cancer registry. Experience in Finland.

Authors:  L Teppo; E Pukkala; M Lehtonen
Journal:  Acta Oncol       Date:  1994       Impact factor: 4.089

6.  Risk factors of breast cancer in Finland.

Authors:  I Soini
Journal:  Int J Epidemiol       Date:  1977-12       Impact factor: 7.196

  6 in total
  39 in total

Review 1.  Cosmic rays: are air crew at risk?

Authors:  M K Lim
Journal:  Occup Environ Med       Date:  2002-07       Impact factor: 4.402

2.  Breast cancer risk among Finnish cabin attendants: a nested case-control study.

Authors:  K Kojo; E Pukkala; A Auvinen
Journal:  Occup Environ Med       Date:  2005-07       Impact factor: 4.402

3.  Cancer mortality among German aircrew: second follow-up.

Authors:  Hajo Zeeb; Gaël P Hammer; Ingo Langner; Thomas Schafft; Sabrina Bennack; Maria Blettner
Journal:  Radiat Environ Biophys       Date:  2009-10-16       Impact factor: 1.925

4.  The potential influence of the microbiota and probiotics on women during long spaceflights.

Authors:  Camilla Urbaniak; Gregor Reid
Journal:  Womens Health (Lond)       Date:  2016-02-22

5.  Risk of breast cancer is also increased among retired US female airline cabin attendants.

Authors:  D Wartenberg; C P Stapleton
Journal:  BMJ       Date:  1998-06-20

6.  Risk of breast cancer among female airline cabin attendants. Findings may have been due to exposure to cosmic radiation or recall bias.

Authors:  P Badrinath; S Ramaiah
Journal:  BMJ       Date:  1999-01-09

7.  Disconnected circadian and cell cycles in a tumor-driven cell line.

Authors:  Julie S Pendergast; Mijung Yeom; Bryan A Reyes; Yoshihiro Ohmiya; Shin Yamazaki
Journal:  Commun Integr Biol       Date:  2010-11-01

8.  Validation of a light questionnaire with real-life photopic illuminance measurements: the Harvard Light Exposure Assessment questionnaire.

Authors:  Archna Bajaj; Bernard Rosner; Steven W Lockley; Eva S Schernhammer
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2011-07       Impact factor: 4.254

9.  Circadian genes and breast cancer susceptibility in rotating shift workers.

Authors:  Genevieve M Monsees; Peter Kraft; Susan E Hankinson; David J Hunter; Eva S Schernhammer
Journal:  Int J Cancer       Date:  2012-09-07       Impact factor: 7.396

10.  Incidence of cancer among Nordic airline pilots over five decades: occupational cohort study.

Authors:  Eero Pukkala; Rafael Aspholm; Anssi Auvinen; Harald Eliasch; Maryanne Gundestrup; Tor Haldorsen; Niklas Hammar; Jón Hrafnkelsson; Pentti Kyyrönen; Anette Linnersjö; Vilhjálmur Rafnsson; Hans Storm; Ulf Tveten
Journal:  BMJ       Date:  2002-09-14
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