Literature DB >> 7547251

Gene methylation of oestrogen and epidermal growth factor receptors in neoplastic and perineoplastic breast tissues.

E Petrangeli1, C Lubrano, L Ravenna, A Vacca, M R Cardillo, L Salvatori, F Sciarra, L Frati, A Gulino.   

Abstract

Oestrogen receptor (ER) and epidermal growth factor receptor (EGFR) gene methylation was evaluated in neoplastic and perineoplastic breast tissues from 20 patients. In both tissues, ER gene methylation was inversely correlated with protein levels, while EGFR gene methylation was not. A preferential ER gene hypomethylation was found in neoplastic tissues, suggesting a significant role in neoplastic transformation.

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Year:  1995        PMID： 7547251      PMCID： PMC2034049          DOI： 10.1038/bjc.1995.444

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  15 in total

Review 1.  CpG-rich islands and the function of DNA methylation.

Authors:  A P Bird
Journal:  Nature       Date:  1986 May 15-21       Impact factor: 49.962

2.  Hypomethylation of DNA from benign and malignant human colon neoplasms.

Authors:  S E Goelz; B Vogelstein; S R Hamilton; A P Feinberg
Journal:  Science       Date:  1985-04-12       Impact factor: 47.728

3.  Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A.

Authors:  S Green; P Walter; V Kumar; A Krust; J M Bornert; P Argos; P Chambon
Journal:  Nature       Date:  1986 Mar 13-19       Impact factor: 49.962

Review 4.  DNA methylation and gene activity.

Authors:  W Doerfler
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

5.  Identification of a polypeptide secreted by human breast cancer cells (MCF-7) as the human estrogen-responsive gene (pS2) product.

Authors:  K Mori; R Fujii; N Kida; M Ohta; K Hayashi
Journal:  Biochem Biophys Res Commun       Date:  1988-08-30       Impact factor: 3.575

6.  A novel type of secondary modification of two CCGG residues in the human gamma delta beta-globin gene locus.

Authors:  L H van der Ploeg; J Groffen; R A Flavell
Journal:  Nucleic Acids Res       Date:  1980-10-24       Impact factor: 16.971

7.  Epidermal growth factor-binding sites, present in normal human and rat pituitaries, are absent in human pituitary adenomas.

Authors:  P Birman; M Michard; J Y Li; F Peillon; D Bression
Journal:  J Clin Endocrinol Metab       Date:  1987-08       Impact factor: 5.958

8.  Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells.

Authors:  P P Di Fiore; J H Pierce; T P Fleming; R Hazan; A Ullrich; C R King; J Schlessinger; S A Aaronson
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582

9.  Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

Authors:  S Ishii; Y H Xu; R H Stratton; B A Roe; G T Merlino; I Pastan
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

10.  Estrogen regulation of epidermal growth factor receptor messenger ribonucleic acid.

Authors:  R B Lingham; G M Stancel; D S Loose-Mitchell
Journal:  Mol Endocrinol       Date:  1988-03
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  5 in total

Review 1.  The epidermal growth factor receptor in breast cancer.

Authors:  S B Fox; A L Harris
Journal:  J Mammary Gland Biol Neoplasia       Date:  1997-04       Impact factor: 2.673

Review 2.  Chemoprevention of breast cancer: implications for postmenopausal women.

Authors:  Carol J Fabian; Bruce F Kimler
Journal:  Drugs Aging       Date:  2002       Impact factor: 3.923

3.  Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.

Authors:  Elzbieta Szmida; Pawel Karpiński; Przemyslaw Leszczynski; Tomasz Sedziak; Wojciech Kielan; Paweł Ostasiewicz; Maria M Sasiadek
Journal:  J Appl Genet       Date:  2014-11-01       Impact factor: 3.240

4.  Detecting and monitoring bladder cancer with exfoliated cells in urine.

Authors:  Nannan Li; Lei Wang; Han Liang; Cong Lin; Ji Yi; Qin Yang; Huijuan Luo; Tian Luo; Liwei Zhang; Xiaojian Li; Kui Wu; Fuqiang Li; Ningchen Li
Journal:  Front Oncol       Date:  2022-09-07       Impact factor: 5.738

Review 5.  Obesity and metabolic comorbidities: environmental diseases?

Authors:  Carla Lubrano; Giuseppe Genovesi; Palma Specchia; Daniela Costantini; Stefania Mariani; Elisa Petrangeli; Andrea Lenzi; Lucio Gnessi
Journal:  Oxid Med Cell Longev       Date:  2013-03-18       Impact factor: 6.543
  5 in total

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