Literature DB >> 7529692

Effects of diphenylhydantoin on motor potentials evoked with magnetic stimulation.

N Mavroudakis1, J M Caroyer, E Brunko, D Zegers de Beyl.   

Abstract

We studied the effect of an acute loading dose of diphenylhydantoin (DPH) on motor responses elicited with cortical magnetic stimulation in normal subjects. DPH increased significantly the motor threshold activation of ADM, APB, FDI and biceps. The motor threshold increase was of greater magnitude for the proximal muscle. Spinal soleus alpha-motoneuron pool excitability assessed by H-reflex was increased significantly suggesting that the motor threshold increase is related to a supraspinal effect of the drug. Our study demonstrates that the motor threshold increase observed after DPH administration occurs not only in epileptic patients but also in normal subjects.

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Year:  1994        PMID： 7529692     DOI： 10.1016/0168-5597(94)90149-x

Source DB:  PubMed          Journal:  Electroencephalogr Clin Neurophysiol        ISSN： 0013-4694


  17 in total

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3.  Primary motor cortical metaplasticity induced by priming over the supplementary motor area.

Authors:  Masashi Hamada; Ritsuko Hanajima; Yasuo Terao; Shingo Okabe; Setsu Nakatani-Enomoto; Toshiaki Furubayashi; Hideyuki Matsumoto; Yuichiro Shirota; Shinya Ohminami; Yoshikazu Ugawa
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4.  Mechanisms of deafferentation-induced plasticity in human motor cortex.

Authors:  U Ziemann; M Hallett; L G Cohen
Journal:  J Neurosci       Date:  1998-09-01       Impact factor: 6.167

5.  The effect of lorazepam on the motor cortical excitability in man.

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6.  Modulation of plasticity in human motor cortex after forearm ischemic nerve block.

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Journal:  J Neurosci       Date:  1998-02-01       Impact factor: 6.167

7.  Convergence of human brain mapping tools: neuronavigated TMS parameters and fMRI activity in the hand motor area.

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8.  Excitatory and inhibitory corticospinal responses to transcranial magnetic stimulation in patients with minor to moderate head injury.

Authors:  A V Chistyakov; J F Soustiel; H Hafner; M Trubnik; G Levy; M Feinsod
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-05       Impact factor: 10.154

9.  Reduced excitability of the motor cortex in untreated patients with de novo idiopathic "grand mal" seizures.

Authors:  V Delvaux; G Alagona; P Gérard; V De Pasqua; P J Delwaide; A Maertens de Noordhout
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10.  Evoked motor response thresholds during transcranial magnetic stimulation in patients with symptomatic partial epilepsy.

Authors:  O V Kotova; O V Vorob'eva
Journal:  Neurosci Behav Physiol       Date:  2007-11
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