| Literature DB >> 7524026 |
A Bakin1, J A Kowalak, J A McCloskey, J Ofengand.
Abstract
The number and location of pseudouridine residues in Escherichia coli 16S ribosomal RNA has been determined by a combination of direct and indirect methods. Only one residue was found, at position 516. This site is at the 5'-end of one of the three most highly conserved long sequences of this RNA molecule. A number of experimental findings have strongly implicated this loop in the fidelity of codon recognition by A-site bound tRNA. By virtue of its location, we suggest that psi 516 may also play a role in maintaining the fidelity of protein synthesis.Entities:
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Year: 1994 PMID: 7524026 PMCID: PMC308345 DOI: 10.1093/nar/22.18.3681
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971