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Literature DB >> 7506159

Nimesulide in the treatment of advanced cancer pain. Double-blind comparison with naproxen.

F Toscani¹, M Gallucci, I Scaricabarozzi.

Abstract

The analgesic efficacy and tolerability of nimesulide and naproxen were compared in 68 patients with advanced cancer who needed to be treated with nonsteroidal anti-inflammatory drugs according to the first step of the pharmacological analgesic scale of the WHO. Patients received either nimesulide 200mg or naproxen 500mg twice daily. The analgesic efficacy and tolerability of the 2 drugs appeared to be similar. Both drugs were effective and were associated with a low incidence of adverse reactions.

Entities: Chemical Disease Species

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Year: 1993 PMID： 7506159 DOI： 10.2165/00003495-199300461-00037

Source DB: PubMed Journal: Drugs ISSN： 0012-6667 Impact factor: 9.546

7 in total

1. Estimation of survival time in terminal cancer patients: an impedance to hospice admissions?

Authors: R S Schonwetter; T A Teasdale; P Storey; R J Luchi
Journal: Hosp J Date: 1990

2. Naproxen: a review of its pharmacological properties and therapeutic efficacy and use.

Authors: R N Brogden; R M Pinder; P R Sawyer; T M Speight; G S Avery
Journal: Drugs Date: 1975 Impact factor: 9.546

Review 3. Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states.

Authors: A Ward; R N Brogden
Journal: Drugs Date: 1988-12 Impact factor: 9.546

4. 4-nitro-2-phenoxymethanesulfonanilide (R-805): a chemically novel anti-inflammatory agent.

Authors: K F Swingle; G G Moore; T J Grant
Journal: Arch Int Pharmacodyn Ther Date: 1976-05

5. Sodium naproxen versus sodium diclofenac in cancer pain control.

Authors: V Ventafridda; F Toscani; M Tamburini; O Corli; M Gallucci; A Gottlieb; R Speranza; F De Conno
Journal: Arzneimittelforschung Date: 1990-10

Review 6. Use of non-steroidal anti-inflammatory drugs in the treatment of pain in cancer.

Authors: V Ventafridda; C Fochi; D De Conno; E Sganzerla
Journal: Br J Clin Pharmacol Date: 1980-10 Impact factor: 4.335

7. Naproxen sodium in treatment of bone pain due to metastatic cancer.

Authors: Stanley Levick; Charlotte Jacobs; Demetrius F Loukas; David H Gordon; Frank L Meyskens; K Uhm
Journal: Pain Date: 1988-12 Impact factor: 6.961

7 in total

3 in total