| Literature DB >> 7002189 |
V Ventafridda, C Fochi, D De Conno, E Sganzerla.
Abstract
1 Prostaglandins may precipitate or exacerbate pain and they may be produced by several tumours. 2 Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit prostaglandin synthesis and may also inhibit bone metastases and enhance immune responses. 3 NSAIDs alone or in association with narcotics or psychotropics may not only afford the best pain relief in neoplastic disease, but also modify the progress of the tumour. 4 The effect of NSAIDs on the gastrointestinal tract is generally adverse.Entities:
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Year: 1980 PMID: 7002189 PMCID: PMC1430200 DOI: 10.1111/j.1365-2125.1980.tb01820.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN: 0306-5251 Impact factor: 4.335