Literature DB >> 750114

Absence of IgG lymphocytotoxins in untreated Hodgkin's disease (HD) patients.

D B Jones, E V Elliott, S V Payne, D H Wright.   

Abstract

Six of twenty-three sera (26%) from patients with Hodgkin's disease (HD) contained IgG antibody with an affinity for human lymphocytes and lymphoblastoid cell lines. All sera were negative for complement-dependent and antibody-mediated cell cytotoxicity against human lymphoid cells irrespective of their binding capacity. It is suggested that the antilymphocyte antibodies seen in HD are not of pathogenic significance but are a non-specific consequence of B-cell stimulation.

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Year:  1978        PMID： 750114      PMCID： PMC1537452     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  14 in total

1.  Reversal of cell surface abnormalities of T lymphocytes in hodgkin's disease after in vitro incubation in fetal sera.

Authors:  Z Fuks; S Strober; D P King; H S Kaplan
Journal:  J Immunol       Date:  1976-10       Impact factor: 5.422

2.  T and B lymphocytes and Reed-Sternberg cells in Hodgkin's disease lymph nodes and spleens.

Authors:  S V Payne; D B Jones; D G Haegert; J L Smith; D H Wright
Journal:  Clin Exp Immunol       Date:  1976-05       Impact factor: 4.330

3.  IgG antilymphocyte antibodies in SLE detected by 125I protein A.

Authors:  R C Williams; A D Bankhurst; J D Montaño
Journal:  Arthritis Rheum       Date:  1976 Nov-Dec

4.  Binding of phytohaemagglutinin to serum substances and inhibition of lymphocyte transformation in Hodgkin's disease.

Authors:  P L Amlot; A Unger
Journal:  Clin Exp Immunol       Date:  1976-12       Impact factor: 4.330

5.  Human leukemic "null" cell line (NALL-1).

Authors:  S Hiraki; I Miyoshi; I Kubonishi; Y Matsuda; T Nakayama; H Kishimoto; H Masuji
Journal:  Cancer       Date:  1977-11       Impact factor: 6.860

6.  Anti-lymphocytic globulin in Hodgkin's disease.

Authors:  D B Jones; S V Payne; D H Wright
Journal:  Biomedicine       Date:  1977-07

7.  Lymphocyte reactivity in Hodgkin's disease: a lymphocyte civil war.

Authors:  V T DeVita
Journal:  N Engl J Med       Date:  1973-10-11       Impact factor: 91.245

8.  Labeled staphylococcal protein A as an immunological probe in the analysis of cell surface markers.

Authors:  G Dorval; K I Welsh; H Wigzell
Journal:  Scand J Immunol       Date:  1974       Impact factor: 3.487

9.  Some effects on leukaemic B lymphocytes of antibodies to defined regions of their surface immunoglobulin.

Authors:  F K Stevenson; E V Elliott; G T Stevenson
Journal:  Immunology       Date:  1977-04       Impact factor: 7.397

10.  T and B lymphocyte antigen-positive null cell leukemias.

Authors:  J Kaplan; Y Ravindranath; W D Peterson
Journal:  Blood       Date:  1977-03       Impact factor: 22.113
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  1 in total

1.  Spontaneous and Concanavalin A-induced suppressor activity in control and Hodgkin's disease patients.

Authors:  A N Akbar; D B Jones; D H Wright
Journal:  Br J Cancer       Date:  1984-03       Impact factor: 7.640
  1 in total

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